Results 31 to 40 of about 4,981,556 (256)

Reconsideration of sample size and power calculation for overall survival in cancer clinical trials

Contemporary Clinical Trials Communications, 2018
When designing a cancer clinical trial, it is usual to assume an exponential distribution for a time-to-event outcome such as overall survival (OS). OS is often expressed as the sum of progression-free survival (PFS) and survival post-progression (SPP ...
Inkyung Jung, Hee Jung Ko, Sun Young Rha, Chung Mo Nam   +3 more
doaj   +1 more source

Statistical Modeling using A New Hybrid Form of The Inverted Exponential Distribution with Different Estimation Methods

InPrime, 2022
This paper introduces a new four-parameter distribution called the exponentiated Gompertz generated inverted exponential (EGGIE) distribution. Explicit expressions of the structural properties such as the ordinary and incomplete moments, probability ...
O. D. Adubisi, C. E. Adubisi
doaj   +1 more source

Uniformly Shifted Exponential Distribution

Axioms
The use of life distributions has increased over the past decade, receiving particular attention in recent years, both from a practical and theoretical point of view. Life distributions can be used in a number of applied fields, such as medicine, biology,
Abdulhamid. A. Alzaid, Najla Qarmalah
doaj   +1 more source

The Odds Exponential-Pareto IV Distribution: Regression Model and Application

Entropy, 2020
This article introduces the odds exponential-Pareto IV distribution, which belongs to the odds family of distributions. We studied the statistical properties of this new distribution.
Lamya A. Baharith, Kholod M. AL-Beladi, Hadeel S. Klakattawi   +2 more
doaj   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

The Distribution of Sum, Product and Ratio for the Absolutely Continuous Bivariate Generalized Exponential Random Variables [PDF]

The Egyptian Statistical Journal, 2017
Block and  Basu  bivariate  exponential  distribution is  a  standout  amongst the  most  absolutely continuous  bivariate   technique . This idea can  be  extended to the  generalized  exponential   technique  also.
Hiba Z. Muhammed
doaj   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

The Hybrid Odd Exponential-Exponential Distribution: Statistical Properties and Applications

Tikrit Journal of Administrative and Economic Sciences
In this paper, we study a new statistical distribution called the hybrid odd exponential-exponential distribution (HOE-E distribution for short) we the aim of applying it to real data sets. This new distribution appears as a sub-model of the larger HOEE-
Ghanam ahmed mahdi, Mundher abdaullah khaleel   +1 more
doaj   +1 more source