Results 31 to 40 of about 692,743 (288)
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Complexity, 2021 This paper is concerned with the outer exponential synchronization of the drive-response complex dynamical networks subject to time-varying delays. The dynamics of nodes is complex valued, the interactions among of the nodes are directed, and the two ...
Xuefei Wu, Jianwen Feng, Zhe Nie
doaj +1 more source
Exponential Sums Related to Maass Forms [PDF]
, 2015 We estimate short exponential sums weighted by the Fourier coefficients of a Maass form. This requires working out a certain transformation formula for non-linear exponential sums, which is of independent interest.
Jääsaari, Jesse, Vesalainen, Esa V.
core
Implicit renewal theory for exponential functionals of L\'evy processes
, 2015 We establish a new functional relation for the probability density function of the exponential functional of a L\'evy process, which allows to significantly simplify the techniques commonly used in the study of these random variables and hence provide ...
Arista, Jonas, Rivero, Víctor M.
core +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Large deviations for clocks of self-similar processes [PDF]
, 2014 The Lamperti correspondence gives a prominent role to two random time changes: the exponential functional of a L\'evy process drifting to $\infty$ and its inverse, the clock of the corresponding positive self-similar process.
A. Dembo +19 more
core +4 more sources
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
Exponential functionals of Levy processes
, 2005 This text surveys properties and applications of the exponential functional $\int_0^t\exp(-\xi_s)ds$ of real-valued L\'evy processes $\xi=(\xi_t,t\geq0)$.Comment: Published at http://dx.doi.org/10.1214/154957805100000122 in the Probability Surveys ...
Bertoin, Jean, Yor, Marc
core +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source