Results 81 to 90 of about 7,472,397 (345)

Uniform exponential growth for CAT(0) square complexes [PDF]

Algebraic and Geometric Topology, 2016
In this paper we start the inquiry into proving uniform exponential growth in the context of groups acting on CAT(0) cube complexes. We address free group actions on CAT(0) square complexes and prove a more general statement.
Aditi Kar, M. Sageev
semanticscholar   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

Interplay between RNA‐protein interactions and RNA structures in gene regulation

FEBS Open Bio, EarlyView.
Methodological advances in mapping transcriptome‐wide RNA‐protein interactions and RNA structures have started to uncover the potential of RNP conformations in gene regulation. Competing RNA–RNA, RNA‐protein and protein–protein interactions shape the compaction and function of RNPs throughout their lifetime and may provide novel therapeutic targets in ...
Jenni Rapakko, Mauro Scaravilli, Minna‐Liisa Änkö   +2 more
wiley   +1 more source

Thrombolytic proteins profiling: High‐throughput activity, selectivity, and resistance assays

FEBS Open Bio, EarlyView.
We present optimized biochemical protocols for evaluating thrombolytic proteins, enabling rapid and robust screening of enzymatic activity, inhibition resistance, and fibrin affinity, stimulation, and selectivity. The outcome translates to key clinical indicators such as biological half‐life and bleeding risk. These assays streamline the development of
Martin Toul, Alan Strunga, Jiri Damborsky, Zbynek Prokop   +3 more
wiley   +1 more source

Dewetting of Glassy Polymer Films

, 2002
Dynamics and morphology of hole growth in a film of power hardening viscoplastic solid (yield stress ~ [strain-rate]^n) is investigated. At short-times the growth is exponential and depends on the initial hole size. At long-times, for n > 1/3, the growth
A. Oron, A. S. Khan, Ashutosh Sharma, B. Crist, C. Redon, F. Brochard-Wyart, F. Saulnier, G. Reiter, J. L. Forrest, J. L. Forrest, J. L. Keddie, K. Jacobs, M. A. Sapid, S. Kawana, Vijay Shenoy   +14 more
core   +1 more source

Rethinking the Concept of Long-Run Economic Growth [PDF]

This paper argues that growth theory needs a more general “regularity” concept than that of exponential growth. This opens up for considering a richer set of parameter combinations than in standard growth models.
Christian Groth, Karl-Josef Koch, Thomas M. Steger   +2 more
core   +3 more sources

SmallTalk: a novel small‐sized fusion tag for peptide expression and purification

FEBS Open Bio, EarlyView.
The SmallTalk fusion tag allows for the efficient expression and purification of soluble recombinant proteins or peptides in Escherichia coli. Testing with SmallTalk‐GFP confirmed that the proteins were soluble and folded correctly, while SmallTalk‐Bin1b maintained its antimicrobial activity against various bacterial isolates. This streamlined workflow
Atika Tariq, Nestor G. Casillas‐Vega, Alma Gomez‐Loredo, Xristo Zarate   +3 more
wiley   +1 more source

Tubular cluster algebras II: Exponential growth [PDF]

Journal of Pure and Applied Algebra, 2013
Among the mutation finite cluster algebras the tubular ones are a particularly interesting class. We show that all tubular (simply laced) cluster algebras are of exponential growth by two different methods: first by studying the automorphism group of the corresponding cluster category and second by giving explicit sequences of mutations.
Barot, M., Geiss, Ch., Jasso, G.
openaire   +3 more sources

Analysis of Treacher Collins syndrome 4‐associated mutations in Schizosaccharomyces pombe

FEBS Open Bio, EarlyView.
Fission yeast models carrying Treacher Collins syndrome type 4‐associated mutations reveal that impaired processivity of RNA polymerase I leads to defective rRNA transcription. This study highlights the essential role of a conserved arginine residue in Pol I elongation and provides mechanistic insight into the pathogenesis of ribosomopathies.
Kei Kawakami, Hiroaki Kato
wiley   +1 more source

Metastasis Initiation Precedes Detection of Primary Cancer—Analysis of Metastasis Growth in vivo in a Colorectal Cancer Test Case

Frontiers in Physiology, 2020
Most cases of deaths from colorectal cancer (CRC) result from metastases, which are often still undetectable at disease detection time. Even so, in many cases, shedding is assumed to have taken place before that time. The dynamics of metastasis formation
Gili Hochman, Einat Shacham-Shmueli, Stephen P. Raskin, Sara Rosenbaum, Svetlana Bunimovich-Mendrazitsky   +4 more
doaj   +1 more source