Results 81 to 90 of about 833,509 (313)
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Computing a matrix function for exponential integrators
Journal of Computational and Applied Mathematics, 2003 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire +1 more source
Degenerate exponential integral function and its properties
Arab Journal of Mathematical Sciences, 2022 PurposeIn this paper, the author introduces a degenerate exponential integral function and further studies some of its analytical properties. The new function is a generalization of the classical exponential integral function and the properties established are analogous to those satisfied by the classical function.Design/methodology/approachThe methods
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LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
Journal of Marine Science and EngineeringThe conventional-speed Sliding Mode Controller (SMC) for ship PM propulsion motors, which employs exponential reaching laws and linear sliding surface functions, demonstrates susceptibility to oscillatory phenomena.
Xi Wang +5 more
doaj +1 more source
Unified integral associated with the generalized V-function
Advances in Difference Equations, 2020 In this paper, we present two new unified integral formulas involving a generalized V-function. Some interesting special cases of the main results are also considered in the form of corollaries.
S. Chandak +2 more
doaj +1 more source
Sharp Exponential Integrability for Traces of Monotone Sobolev Functions [PDF]
Nagoya Mathematical Journal, 2008 AbstractWe answer a question posed in [12] on exponential integrability of functions of restricted n-energy. We use geometric methods to obtain a sharp exponential integrability result for boundary traces of monotone Sobolev functions defined on the unit ball.
Pankka, Pekka +2 more
openaire +3 more sources
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Theoretical Foundations and Mathematical Formalism of the Power-Law Tailed Statistical Distributions
Entropy, 2013 We present the main features of the mathematical theory generated by the √ κ-deformed exponential function expκ(x) = ( 1 + κ2x2 + κx)1/κ, with 0 ≤ κ < 1, developed in the last twelve years, which turns out to be a continuous one parameter deformation of ...
Giorgio Kaniadakis
doaj +1 more source
SmallTalk: a novel small‐sized fusion tag for peptide expression and purification
FEBS Open Bio, EarlyView.The SmallTalk fusion tag allows for the efficient expression and purification of soluble recombinant proteins or peptides in Escherichia coli. Testing with SmallTalk‐GFP confirmed that the proteins were soluble and folded correctly, while SmallTalk‐Bin1b maintained its antimicrobial activity against various bacterial isolates. This streamlined workflow
Atika Tariq +3 more
wiley +1 more source