Results 31 to 40 of about 15,801 (247)

EXPONENTIAL INTEGRABILITY OF STOCHASTIC CONVOLUTIONS [PDF]

open access: yesJournal of the London Mathematical Society, 2003
Let \(W\) be a Wiener process in a Hilbert space (possibly cylindrical), \(U(t,s)\) be convolution operators in this space (in particular, \(U(t,s)=e^{(t-s)A}\) where \(e^{tA}\) is a \(C_0\)-semigroup). The estimate \[ E\exp\left(\lambda\sup_t\left\|\int_0^tU(t,s)\psi(s)dW(s)\right\|^2\right)\leq K \] is derived in several variants.
Seidler, Jan, Sobukawa, Takuya
openaire   +2 more sources

Magnus integrators on multicore CPUs and GPUs

open access: yes, 2018
In the present paper we consider numerical methods to solve the discrete Schr\"odinger equation with a time dependent Hamiltonian (motivated by problems encountered in the study of spin systems). We will consider both short-range interactions, which lead
Auer, N.   +3 more
core   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Geometric integration of non-autonomous Hamiltonian problems [PDF]

open access: yes, 2014
Symplectic integration of autonomous Hamiltonian systems is a well-known field of study in geometric numerical integration, but for non-autonomous systems the situation is less clear, since symplectic structure requires an even number of dimensions.
Marthinsen, Håkon, Owren, Brynjulf
core  

An introduction to Lie group integrators -- basics, new developments and applications

open access: yes, 2012
We give a short and elementary introduction to Lie group methods. A selection of applications of Lie group integrators are discussed. Finally, a family of symplectic integrators on cotangent bundles of Lie groups is presented and the notion of discrete ...
Blanes   +70 more
core   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Functionally-fitted energy-preserving integrators for Poisson systems

open access: yes, 2017
In this paper, a new class of energy-preserving integrators is proposed and analysed for Poisson systems by using functionally-fitted technology. The integrators exactly preserve energy and have arbitrarily high order.
Wang, Bin, Wu, Xinyuan
core   +1 more source

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

open access: yesMolecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone   +11 more
wiley   +1 more source

Efficient geometric integrators for nonadiabatic quantum dynamics. II. The diabatic representation

open access: yes, 2019
Exact nonadiabatic quantum evolution preserves many geometric properties of the molecular Hilbert space. In a companion paper [S. Choi and J. Van\'{\i}\v{c}ek, 2019], we presented numerical integrators of arbitrary-order of accuracy that preserve these ...
Choi, Seonghoon   +2 more
core   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

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