Results 241 to 250 of about 25,940 (295)

Identification of a Nonribosomal Peptide Analog With Activity Against Multiple Gram‐Positive Bacteria via a Synthetic Bioinformatic Natural Product Discovery Approach

Advanced Science, EarlyView.
The genome of Rhodococcus erythropolis D‐1 was analyzed by bioinformatic tools to mine a novel nonribosomal peptide synthetase (NRPS) gene cluster. A nonribosomal peptide analog ZURJC5 associated with the NRPS was chemically synthesized. Through structure‐activity relationship studies, ZURJC28 was ultimately obtained and showed antibacterial activity ...
Keyi Chen, Jiayi Liang, Yujia Wu, Jianan Xu, Yi Liu, Wenguang Wang, Xinhang Jiang, Benjie Gao, Yueyue Wang, Hui Jiang   +9 more
wiley   +1 more source

Dynamic Analysis of Bi-Stable Galloping Energy Harvesters Under Random Excitation. [PDF]

Micromachines (Basel)
Zhang Y, Qin R, Zheng K, Zhang J.
europepmc   +1 more source

Single‐Cell RNA Editing Identifies T Cell ADAR1 as a Key Regulator of Immune Exhaustion and Anti‐PD‐1 Resistance in Colorectal Cancer

Advanced Science, EarlyView.
Single‐cell RNA editing analysis identifies ADAR1 as a regulator of dysfunctional T cell states in colorectal cancer. Elevated ADAR1 activity promotes T cell exhaustion and impairs antitumor immunity partly through TGF‐β‐SMAD signaling, contributing to anti‐PD‐1 resistance and highlighting T cell ADAR1 as a potential therapeutic target and biomarker ...
Da Kang, Song‐Zuo Xie, Yong‐Zhou Luo, Xin‐Pei Deng, Xi‐Rong Tan, Ze‐Geng Chen, Ling‐Xing Zeng, Gong Chen, Pei‐Rong Ding, Zhi‐Zhong Pan, Rong‐Xin Zhang   +10 more
wiley   +1 more source

Simplified dosimetry using two-time-point kinetic modeling of ¹²⁴I-MIBG PET for ¹³¹I-MIBG therapy in neuroblastoma. [PDF]

Med Phys
Wang Y, Huh Y, Matthay KK, Vo KT, Pampaloni MH, DuBois SG, Seo Y.   +6 more
europepmc   +1 more source

Optimal Control Method for Microgrid Distributed Generation Based on Multi-Agent Adaptive Decision-Making. [PDF]

Sensors (Basel)
Mai H, Teng Q, Wang X.
europepmc   +1 more source

Zone of inhibition prediction in silver nanoparticle antimicrobial activity via physics-guided liquid state machine. [PDF]

Biomater Biosyst
Dechakupt T, Akkawong C, Bardeeniz S, Jitapunkul K, Panjapornpon C.   +4 more
europepmc   +1 more source

A review and evaluation of doubly robust approaches for estimating average treatment effects. [PDF]

Behav Res Methods
Zhang J, Lüdtke O, Robitzsch A.
europepmc   +1 more source

Salivary glands as the primary dose-limiting organ: an integrated dosimetry, efficacy, and toxicity study of ²²⁵Ac-PSMA-617 in prostate cancer xenografts. [PDF]

Front Pharmacol
Cai C, Li P, Wang Z, Chen Y, Qu C, Jin C, Kong X.   +6 more
europepmc   +1 more source

Label-free optical observation of disordered-to-ordered transitions in single intrinsically disordered proteins. [PDF]

NPJ Biosens
Zargarbashi S, Dominguez C, Peters M, Yousefi A, Munday S, Wang Y, Chatterjee S, Hudson AJ, Gordon R, Mellor CJ, Xu L, Rahmani M, Ying C.   +12 more
europepmc   +1 more source