Results 191 to 200 of about 630,695 (296)

O-GlcNAc modulation of nuclear pore complexes orchestrates mRNA export efficiency. [PDF]

Proc Natl Acad Sci U S A
Junod SL, Rush C, Tingey M, Yang W.
europepmc   +1 more source

Human iPSC‐Derived Mononuclear Phagocytes Improve Cognition and Neural Health across Multiple Mouse Models of Aging and Alzheimer's Disease

Advanced Science, EarlyView.
Short‐term intravenous treatments with iPSC‐derived mononuclear phagocytes (iMPs) improve cognitive decline and neural health in two mouse models of aging and in the 5xFAD mouse model of Alzheimer's disease. iMPs reduce levels of serum amyloid proteins that increase in aging and improve the health of hippocampal microglia and mossy cells.
V. Alexandra Moser, Luz Jovita Dimas‐Harms, Rachel M. Lipman, Jake Inzalaco, Shaughn Bell, Michelle Alcantara, Erikha Valenzuela, George Lawless, Simion Kreimer, Sarah J. Parker, Helen S. Goodridge, Clive N. Svendsen   +11 more
wiley   +1 more source

Factors associated with the export of traditional Chinese medicinal products: A stochastic frontier analysis. [PDF]

PLoS One
Chen Y, Zhou S, Pei Z, Zhao W, Yang J, Hu Y, Feng X, Xu M.   +7 more
europepmc   +1 more source

Are mangroves drivers or buffers of coastal acidification? Insights from alkalinity and dissolved inorganic carbon export estimates across a latitudinal transect

, 2016
J. Sippo, D. Maher, D. Tait, Ceylena J. Holloway, I. Santos   +4 more
semanticscholar   +1 more source

Regular versus Irregular Exercise Differentially Modulates Hippocampal‐Hepatic Acetylcholine Flux to Coordinate Fear Memory Extinction and Liver Inflammation

Advanced Science, EarlyView.
Ma et al. report the hippocampal and hepatic acetylcholine (ACh) levels are differently modulated by regular versus irregular exercise, which contributes to coordinate hippocampal astrocyte activity and hepatic FBXL6high neutrophil recruitment. This ACh‐modulated brain‐liver circuit links the effects of exercise on fear memory extinction and liver ...
Pengjiao Ma, Kuan Zhang, Long Yi, Chuanyan Yang, Hedong Lang, Jianbin Sun, Jin Li, Qian Bai, Yuhang He, Shuang‐Shuang Dai, Man‐Tian Mi   +10 more
wiley   +1 more source

A yeast-based in vivo assay complements in vitro and in silico approaches to characterize sterol-binding by Saccharomyces cerevisiae Lam/Ltc proteins. [PDF]

J Biol Chem
El Atab O, Gupta B, Han Z, Darwiche R, Cottier S, Stribny J, Schneiter R.   +6 more
europepmc   +1 more source

TBC1D22B Regulates ER‐to‐Golgi Trafficking via RAB1B Inactivation and Promotes Oncogenic Programs in Breast Cancer

Advanced Science, EarlyView.
TBC1D22B, a Golgi‐localized RabGAP linked to poor prognosis in breast cancer, inhibits ER‐to‐Golgi transport via RAB1B inactivation. This disrupts secretion, drives oncogenic transcriptional reprogramming, and promotes tumor growth. These findings indicate that TBC1D22B connects membrane trafficking to transcriptional control and cancer progression ...
Flavia Martino, Mariadomenica Lupi, Alessandra Murabito, Fabio Bedin, Giulia Villari, Linda Andreoli, Stefano Freddi, Bronislava Matoskova, Rosa Pennisi, Stella Fontana, Amir Fardin, Gaelle Boncompain, Franck Perez, Federico Bussolino, Alessandro Cuomo, Sara Sigismund, Letizia Lanzetti   +16 more
wiley   +1 more source

A β-cap on the FliPQR protein-export channel acts as the cap for initial flagellar rod assembly. [PDF]

Proc Natl Acad Sci U S A
Kinoshita M, Miyata T, Makino F, Imada K, Namba K, Minamino T.   +5 more
europepmc   +1 more source

Potentiating Cerebral Perfusion Normalizes Glymphatic Dynamics in Systemic Inflammation

Advanced Science, EarlyView.
LPS‐induced systemic inflammation increases glymphatic influx but delays cervical lymphatic drainage, accompanied by AQP4 depolarization and impaired glymphatic clearance. Enhancing cerebral blood flow via the inotropic agent levosimendan effectively restored AQP4 polarization, improving glymphatic flux and amyloid‐β clearance.
Ruoyu Zhao, Bin Sun, Pengju Wei, Yingying Sun, Qianyan He, Kejia Zhang, Jun Lu, Shoujun Zhu, Yi Yang, Zhenni Guo   +9 more
wiley   +1 more source

Stability of the marine nitrogen cycle over the past 165 million years. [PDF]

Nat Commun
Godfrey LV, Omta AW, Tziperman E, Li X, Hu Y, Falkowski PG.   +5 more
europepmc   +1 more source