Results 231 to 240 of about 719,145 (360)
ACLY is vital for early embryo development. IGF‐1 activates AKT to phosphorylate ACLY, driving its nuclear localization and recruitment of HATs (P300/HAT1), boosting acetyl‐CoA production and histone acetylation for transcriptional activation. Conversely, ACLY deficiency (via knockdown, knockout, or AKT inhibition) reduces nuclear acetyl‐CoA, disrupts ...
Yerong Ma+18 more
wiley +1 more source
Influence of long-term anthropogenic nitrogen input and its legacy on riverine output. [PDF]
Cao M, Gao W, Cai Y.
europepmc +1 more source
MYC is a transcription factor (TF) that binds DNA near transcriptional start sites (TSSs) and within enhancer elements. Here, unappreciated sites of MYC binding in the vicinity of transcriptional end sites (TESs) of many genes in multiple cell types in association with numerous other TFs are described previously.
Huabo Wang+5 more
wiley +1 more source
Impact of exporter proteins and their engineering on the productivity of Corynebacterium. [PDF]
Kinose K, Shinoda K, Kawasaki H.
europepmc +1 more source
This study presents a novel portable grasp‐assist glove, weighing only 47 g. The glove integrates smart adhesive pads and a hands‐free control interface based on IMU, designed to aid rheumatic patients with impaired hand function. The system enables switchable adhesion with independent control and detection of user release intent.
Shiqiang Wang+11 more
wiley +1 more source
Human perturbations to mercury in global rivers. [PDF]
Peng D+12 more
europepmc +1 more source
TWO ASPECTS OF THE EXPORT OF MANUFACTURED GOODS FROM DEVELOPING COUNTRIES [PDF]
Atsushi Murakami
openalex +1 more source
The electron transfer flux in CPR‐P450 catalytic system is systematically engineered through: i) enhancing electron transfer rate by redesigning the putative electron transfer pathway of CPR; ii) improving electron‐receiving rate by evolving the heme domain of tryptophan‐5‐hydroxylase (T5H); iii) enlarging electron supply by fine‐tuning NADPH synthesis.
Wenzhao Xu+4 more
wiley +1 more source