Results 251 to 260 of about 1,507,753 (296)

Endothelial PDGF Signaling Dysregulation Impairs Testicular Interstitial Homeostasis in Diabetes

open access: yesAdvanced Science, EarlyView.
Testicular endothelial cells (TECs) function as central signaling hubs that coordinate interstitial homeostasis. Diabetes disrupts TEC‐derived PDGF signaling, silences the JUND‐MCL1 survival program in Leydig cells, and impairs peritubular function, leading to fibrosis and testosterone insufficiency.
Wenxiu Zhang   +14 more
wiley   +1 more source

PVNCRF Neurons Regulate Migraine‐Like Allodynia by Activating CRFR2 on Spinal Trigeminal Caudalis Glutamatergic Neurons

open access: yesAdvanced Science, EarlyView.
Paraventricular CRF neurons in the hypothalamus project to glutamatergic neurons of the spinal trigeminal caudal nucleus, enhancing neuronal activation and CRFR2 signaling. This pathway increases CRF release and excitatory drive, promoting central sensitization and migraine‐related behaviors. Targeting the PVN–SP5C circuit provides a potential strategy
Jiang Bian   +13 more
wiley   +1 more source

Commodity risk assessment of <i>Salix</i> unrooted cuttings from the UK. [PDF]

open access: yesEFSA J
EFSA Panel on Plant Health (PLH)   +29 more
europepmc   +1 more source

The FliI ATPase couples ATP hydrolysis to substrate switching in bacterial flagellar type-III secretion. [PDF]

open access: yesmBio
Einenkel R   +5 more
europepmc   +1 more source

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