Results 281 to 290 of about 719,145 (360)

The TerC family metal chaperone MeeY enables surfactin export in <i>Bacillus subtilis</i>. [PDF]

J Bacteriol
He B, Sachla AJ, Ruesewald SB, Kearns DB, Helmann JD.   +4 more
europepmc   +1 more source

A Nanostructured Ru‐Mn‐Nb Alloy with Oxygen‐Enriched Boundaries for Ampere‐Level Hydrogen Evolution

Advanced Science, EarlyView.
Ru62Mn12Nb21O5 medium‐entropy alloy with a crystal‐crystal dual‐phase structure is deposited on a carbon cloth substrate by the magnetron sputtering method. The oxygen‐rich interface induced by the rich Mn phase and the poor Mn phase optimized the electronic structure of the catalyst, adjusted the adsorption and desorption processes of intermediates ...
Jie Li, Xue Wang, Jun Yu, Kai Xu, Zhe Jia, Hongkun Li, Lei Ren, Yiyuan Yang, Keke Chang, Yangyang Li, Xiangfa Liu, Jian Lu, Sida Liu   +12 more
wiley   +1 more source

On the coincidence of weather extremes and geopolitical conflicts: Risk analysis in regional food markets. [PDF]

PLoS One
Arreyndip NA, Pal JS.
europepmc   +1 more source

The GRK2/AP‐1 Signaling Axis Mediates Vascular Endothelial Dysfunction and Atherosclerosis Induced by Oscillatory Low Shear Stress

Advanced Science, EarlyView.
This study highlights GRK2 is a central mediator in OSS‐induced endothelial dysfunction. OSS activates GPCRs in endothelial cells, leading to GRK2 phosphorylation and the activation of AP‐1. AP‐1 induces inflammation, while also promoting NR4A1 expression and anchoring LKB1 in the nucleus, which suppresses AMPK activity. This cascade causes endothelial
Li‐Da Wu, Yi Shi, Chao‐Hua Kong, Ai‐Qun Chen, Ying Kang, Jun‐Yan Kan, Xiao‐Min Jiang, Peng Chu, Dong‐Chen Wang, Yi‐Fei Lv, Zhi‐Yuan Qian, Zi‐Hao Jiang, Yun‐Wei Chen, Yue Sun, Rui‐Rui Chang, Wen‐Ying Zhou, Yue Gu, Jun‐Xia Zhang, Shao‐Liang Chen   +18 more
wiley   +1 more source

Role of human herpesvirus homologs of infected cell protein 27 (ICP27) in the biogenesis, processing, and maturation of mRNAs. [PDF]

mBio
Soto-Machuca AA, Ortiz GE, Carbone-Schellman J, Pastén-Ferrada IA, Retamal-Díaz A, Kalergis AM, González PA.   +6 more
europepmc   +1 more source

Small Extracellular Vesicles Orchestrate Cisplatin‐Induced Ototoxicity: Potential Biomarker and Targets Discovery

Advanced Science, EarlyView.
Cisplatin causes reactive oxygen species accumulation, leading to apoptosis and inflammation in cochlear hair cells. Small extracellular vesicles primarily derived from the damaged hair cells likely contribute to cisplatin‐induced ototoxicity, carrying a variety of microRNAs and proteins.
Jingru Ai, Shasha Zhang, Mingchen Dai, Pei Jiang, Jingyuan Huang, Hairong Xiao, Yanqin Lin, Xujun Tang, Wei Tong, Jun He, Qiuyue Mao, Yintao Wang, Zixuan Ye, Tian Wang, Renjie Chai   +14 more
wiley   +1 more source

Influenza A virus RNA localisation and the interceding trafficking pathways of the host cell. [PDF]

PLoS Pathog
Bonazza S, Courtney DG.
europepmc   +1 more source

A Smart Single‐Loop‐Mediated Isothermal Amplification Facilitates Flexible SNP Probe Design for On‐Site Rapid Differentiation of SARS‐CoV‐2 Omicron Variants

Advanced Science, EarlyView.
The ssLAMP method amplifies the nucleic acid of pathogen and identifies SNP mutations. By combining the portable detection device with smartphone‐based analysis software, enables rapid, on‐site SNP detection and genotyping of SARS‐Cov‐2 Omicron variants, providing a cost‐effective and field‐deployable solution for precise pathogen identification in ...
Qijie Lin, Hongchao Gou, Xiaoyun Qu, Kaiyuan Jia, Yuhui Deng, Dan Li, Qianyi Cai, Yucen Liang, Xiaozhen Xu, Yanbin Li, Jianhan Lin, Letian Li, Yuhang Jiang, Shouwen Du, Lingcong Deng, Bailing Yan, Ruidong Liu, Chang Li, Jianmin Zhang, Ming Liao   +19 more
wiley   +1 more source

YTHDC1 phase separation drives the nuclear export of m⁶A-modified lncNONMMUT062668.2 through the transport complex SRSF3-ALYREF-XPO5 to aggravate pulmonary fibrosis. [PDF]

Cell Death Dis
Chen S, Wang Y, Zhang J, Liu B, Liu W, Cao G, Li R, Li H, Zhai N, Song X, Zhang S, Lv C.   +11 more
europepmc   +1 more source

Mechanistic Foundations of KRAS‐Driven Tumor Ecosystems: Integrating Crosstalk among Immune, Metabolic, Microbial, and Stromal Microenvironment

Advanced Science, EarlyView.
KRAS mutations dynamically remodel the tumor microenvironment (TME), fostering immunosuppression, metabolic symbiosis, and stromal plasticity. This review dissects how oncogenic KRAS variants sculpt TME networks and explores actionable vulnerabilities. Emerging strategies combining KRAS inhibitors and TME‐editing approaches offer potential to dismantle
Jiayao Ma, Shenao Fu, Jun Tan, Ying Han, Yihong Chen, Xiangying Deng, Hong Shen, Shan Zeng, Yinghui Peng, Changjing Cai   +9 more
wiley   +1 more source