Results 71 to 80 of about 1,916,844 (345)

Dual Requirement for Yeast hnRNP Nab2p in mRNA poly(A) Tail Length Control and Nuclear Export [PDF]

, 2002
Recent studies of mRNA export factors have provided additional evidence for a mechanistic link between mRNA 3′‐end formation and nuclear export. Here, we identify Nab2p as a nuclear poly(A)‐binding protein required for both poly(A) tail length control ...
Anderson, James T., Dheur, Sonia, Hector, Ronald E., Minvielle‐Sebastia, Lionel, Non, Priscilla J., Nykamp, Keith R., Swanson, Maurice S., Urbinati, Carl R., Wilson, Scott M.   +8 more
core   +3 more sources

Automatic Object Detection in Radargrams of Multi-Antenna GPR Systems Based on Simulation Data for Railway Infrastructure Analysis

Applied Sciences
Ground-penetrating radar (GPR) is a non-invasive technology that uses electromagnetic pulses for subsurface exploration. In the railroad sector, it is crucial to assessing soil layers and infrastructure, offering insights into soil stratification and ...
Lukas Lahnsteiner, David Größbacher, Martin Bürger, Gerald Zauner   +3 more
doaj   +1 more source

Activation of NF‐κB Signaling by Optogenetic Clustering of IKKα and β

Advanced Biology, EarlyView.
This study presents an optogenetic approach for graded clustering of eGFP‐fused proteins using an eGFP‐specific nanobody and engineered Cryptochrome 2 variants. The method enables potent, reversible activation of NF‐κB signaling via endogenous pathways, as confirmed by RNA sequencing. This versatile system provides a spatially and temporally controlled
Alexandra Anna Maria Fischer, Markus Michael Kramer, Miguel Baños, Merlin Moritz Grimm, Manfred Fliegauf, Bodo Grimbacher, Gerald Radziwill, Sven Rahmann, Wilfried Weber   +8 more
wiley   +1 more source

The Entrepreneurial State Goes to Europe [PDF]

, 1993
This article investigates state-level export programs in response to the emerging new economic and political regime of Europe 1992. Little related export promotion activity is found, even in states reputed to have the most active entrepreneurial policies.
Carroll, John, Hudson, William E., Hyde, Mark   +2 more
core   +1 more source

Naringin and temozolomide combination suppressed the growth of glioblastoma cells by promoting cell apoptosis: network pharmacology, in-vitro assays and metabolomics based study

Frontiers in Pharmacology
Introduction: Glioblastoma, which affects a large number of patients every year and has an average overall lifespan of around 14.6 months following diagnosis stands out as the most lethal primary invasive brain tumor.
Priya Bisht, Surendra Rajit Prasad, Khushboo Choudhary, Ruchi Pandey, Dande Aishwarya, Vulli Aravind, Peraman Ramalingam, Ravichandiran Velayutham, Ravichandiran Velayutham, Nitesh Kumar   +9 more
doaj   +1 more source

Plastic pollution in the marine environment

Heliyon, 2020
Plastic pollution is recognized as a severe anthropogenic issue in the coastal and marine ecosystems across the world. Unprecedented and continuous accumulation of growing plastic contaminants into any respective aquatic ecosystem by the anthropogenic ...
G.G.N. Thushari, J.D.M. Senevirathna
doaj   +1 more source

β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations

Advanced Biology, Volume 9, Issue 3, March 2025.
Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio, B. Spedicato, G. Corallo, A. Inguscio, M. Greco, D. Musarò, D. Vergara, A. F. Muro, G. De Sabbata, L. R. Soria, N. Brunetti Pierri, M. Maffia   +11 more
wiley   +1 more source

Study of Increasing the Export Potential of Indonesia Wood Pellets as a Source of the Renewable Biomass Energy Source

Jurnal Ilmu Kehutanan, 2018
The world today is beginning to switch from using coal into renewable energy sources. One of them is wood pellets in order to reduce greenhouse gas emissions and increase the use of renewable energy substitute for fossil energy. The major manufacturer of
Victor Tulus Pangapoi Sidabutar
doaj   +1 more source

Retrotransposon Expression Is Upregulated in Adulthood and Suppressed during Regeneration of the Limb in the Axolotl (Ambystoma mexicanum)

Advanced Biology, EarlyView.
The axolotl's remarkable regenerative abilities decline with age, the causes may include the numerous repetitive elements within its genome. This study uncovers how Ty3 retrotransposons and coexpression networks involving muscle and immune pathways respond to aging and regeneration, suggesting that transposons respond to physiological shifts and may ...
Samuel Ruiz‐Pérez, Nicolás Alcaraz, Karla Torres‐Arciga, José Antonio Ocampo‐Cervantes, Alejandra Cervera, Clementina Castro‐Hernández, Cynthia Gabriela Sámano‐Salazar, Ernesto Soto‐Reyes, Rodrigo González‐Barrios   +8 more
wiley   +1 more source

Identification of NPC1 as the target of U18666A, an inhibitor of lysosomal cholesterol export and Ebola infection

eLife, 2015
Niemann‐Pick C1 (NPC1) is a lysosomal membrane protein that exports cholesterol derived from receptor‐mediated uptake of LDL, and it also mediates cellular entry of Ebola virus.
F. Lu, Qiren Liang, Lina Abi-Mosleh, Akash Das, J. D. De Brabander, J. Goldstein, Michael S. Brown   +6 more
semanticscholar   +1 more source