Results 71 to 80 of about 588,610 (312)
Aging and Cancer, EarlyView.Cancer treatment is associated with measurable acceleration of biological aging across epigenetic, telomere, senescence, and immune biomarkers. However, biomarker validation and interventional strategies remain limited, especially in hematologic malignancies, underscoring the need for standardized multi‐omic aging assessments and adequately powered ...
Moataz Ellithi +3 more
wiley +1 more source
Plastic pollution in the marine environment
Heliyon, 2020 Plastic pollution is recognized as a severe anthropogenic issue in the coastal and marine ecosystems across the world. Unprecedented and continuous accumulation of growing plastic contaminants into any respective aquatic ecosystem by the anthropogenic ...
G.G.N. Thushari, J.D.M. Senevirathna
doaj +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw +5 more
wiley +1 more source
Foreign Direct Investment and Export Spillovers: How Do Export Platforms Fare? [PDF]
Should economies that promote themselves as export platforms for FDI be expected to experience relatively high levels of export spillovers from foreign to host-country enterprises?
Julie Sutherland, Frances Ruane
core
Peripheral Neutrophil Activation and Extracellular Trap Formation in Amyotrophic Lateral Sclerosis
Annals of Clinical and Translational Neurology, EarlyView.Markers of neutrophil activation are increased in plasma during ALS, and markers of NET formation associate with ALS survival. ABSTRACT Objectives Peripheral neutrophil levels in amyotrophic lateral sclerosis (ALS) inversely correlate with survival, suggesting a role for neutrophils in disease progression.
Lillia A. Baird +9 more
wiley +1 more source
Export performance of Chinese domestic firms: the role of foreign export spillovers [PDF]
We investigate how the proximity to multinational exporters influences the creation of new export linkages (extensive margin of trade) by domestic firms in China.
PONCET, Sandra, MAYNERIS, Florian
core +2 more sources
Saccharomyces boulardii: a probiotic yeast for gut health and food innovation [PDF]
Microbiology AustraliaSaccharomyces boulardii (S. cerevisiae var. boulardii) is a non-pathogenic yeast recognised as a eukaryotic probiotic. This probiotic is considered safe for use in both adults and children and functions as a biotherapeutic agent due to its antioxidant ...
Leeshika Panapitiya +1 more
doaj +1 more source
Upper Cervical Cord Area as a Biomarker of Conversion to Secondary Progressive Multiple Sclerosis
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective This study assessed whether upper cervical cord area (UCCA) measured on routine brain MRI can serve as a biomarker of conversion to SPMS. Methods This is a single‐center retrospective cohort study of RRMS patients with cross‐sectional and longitudinal analyses of clinical and MRI data. Future SPMS converters were matched by age, sex,
Nabil K. El Ayoubi +8 more
wiley +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Gliomas have undergone a profound redefinition over the past decade, transitioning from morphology‐based entities to biologically coherent diseases defined by molecular alterations. The 2021 WHO Classification of Tumors of the Central Nervous System and its 2022 update formalize this shift, establishing integrated diagnosis as the global ...
Maria Guarnaccia, Sebastiano Cavallaro
wiley +1 more source
Arthritis Care &Research, EarlyView.Objective Rheumatic and musculoskeletal diseases (RMDs) are leading causes of physical disability, necessitating support with activities of daily living. This study describes social care received by patients with RMDs in two disparate regions of England: Salford (urban) and Norfolk (rural).
Mehreen Somro +6 more
wiley +1 more source