Results 241 to 250 of about 1,344,114 (314)

Targeting DAP5 Disrupts Alternate Mode of Translational Initiation in Tregs and Potentiates Antitumor Immunity

open access: yesAdvanced Science, EarlyView.
Regulatory T cells (Tregs) suppress antitumor immunity. This study identifies that the translation scaffold DAP5/eIF4G2 is upregulated in tumor‐infiltrating Tregs (ti‐Tregs). DAP5 mediates an alternate translation mode to sustain CD25 and MCL‐1 expression, which is critical for ti‐Treg stability and survival in the tumor microenvironment.
Xiaojiang Lai   +12 more
wiley   +1 more source

AstroID resource: a scalable, relational database structure for longitudinal biomarker discovery. [PDF]

open access: yesJ Immunother Cancer
Will EM   +18 more
europepmc   +1 more source

Intracellular trafficking SNARE protein, syntaxin-6, modifies prion cellular phenotypes and risk of disease development in vivo. [PDF]

open access: yesActa Neuropathol
Hill E   +22 more
europepmc   +1 more source

Synthetic nanoparticles for cell-type specific, spatially resolved loading and export of miRNAs in neural cells

open access: yes
Mignanelli M   +13 more
europepmc   +1 more source

Synthetic nanoparticles for cell-type specific, spatially resolved miRNA loading and export in neural cells

open access: yes
Mignanelli M   +13 more
europepmc   +1 more source

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