Results 161 to 170 of about 533,596 (298)
Inefficiency in the German Mechanical Engineering Sector [PDF]
This paper aims to examine the relative efficiency of German engineering firms using a sample of roughly 23,000 observations between 1995 and 2004. As these firms had been successful in the examination period in terms of output- and export-growth, it is ...
Alexander Schiersch
core
Endocytic Control of Cell‐Autonomous and Non‐Cell‐Autonomous Functions of p53
Advanced Science, EarlyView.NUMB Ex3‐containing isoforms localize to the plasma membrane, where they recruit p53 through SNX9 and direct it to multivesicular bodies and exosomes. Exported p53 is taken up by neighboring cells and activates nuclear programs, revealing an intercellular, exosome‐based pathway that might help establish a tumor‐suppressive microenvironment.
Roberta Cacciatore +20 more
wiley +1 more source
O-GlcNAc modulation of nuclear pore complexes orchestrates mRNA export efficiency. [PDF]
Proc Natl Acad Sci U S AJunod SL, Rush C, Tingey M, Yang W.
europepmc +1 more source
Advanced Science, EarlyView.TRMT6‐mediated m1A modification in CDK9 mRNA enhances its mRNA stability and translation efficiency, thereby increasing the protein levels of CDK9. Upregulated CDK9 promotes the progression of HCC by elevating the levels of oncogenic factors including p‐STAT3, MCL1, and BCL‐2. On the other hand, CDK9 phosphorylates TARDBP at Ser254 to activate HBV core
Rui Zhang +12 more
wiley +1 more source
Input and Quality Controls: A Stochastic Frontier Analysis of Bangladesh’s Industrial Trawl Fishery [PDF]
This paper examines the effectiveness of different management tools, particularly input and quality controls on Bangladesh’s industrial trawl fishery. Results show that the efficiency of industrial trawl fishery comes from multiple owner managed vessels,
Chowdhury, Nanzeen Kawshar +2 more
core +1 more source
Zinc Exposure Causes Disulfidptosis to Induce Miscarriage by Up‐Regulating GATA1/METTL1/SLC7A11 Axis
Advanced Science, EarlyView.Zn exposure up‐regulates GATA1, promoting GATA1‐mediated METTL1 and SLC7A11 transcription. It also enhances METTL1‐mediated m7G modification on SLC7A11 mRNA, increasing SLC7A11 mRNA stability. Ultimately, Zn exposure up‐regulates SLC7A11 at both transcriptional and post‐transcriptional levels, causing disulfidptosis. Knockdown of murine Slc7a11, Gata1,
Wenxin Huang +16 more
wiley +1 more source
China, India, and the future of the world economy : fierce competition or shared growth? [PDF]
Although both China and India are labor-abundant and dependant on manufactures, their export mixes are very different. Only one product-refined petroleum-appears in the top 25 products for both countries, and services exports are roughly twice as ...
Dimaranan, Betina +2 more
core
Economic efficiency of food export of Moldova
, 2012 Economic theory suggests that export expansion generates a resource allocation improve efficiency and increase productive output by capital accumulation. Export growth causes increasing openness of the economy, so those saving will be able to absorb more quickly by imitation technologies advanced counters.
openaire +1 more source
Improved Systemic Immunochemotherapy Employing an Oxaliplatin‐TLR7/8 Agonist Prodrug Strategy
Advanced Science, EarlyView.A platinum(IV) prodrug is developed to systemically deliver the TLR7/8 agonist gardiquimod. Tumor‐targeting is mediated by an albumin‐binding maleimide, which limits premature complex activation. Ox‐Gardi‐Mal accumulates specifically in the tumor, where it activates the immune system.
Michael Gutmann +15 more
wiley +1 more source