Results 71 to 80 of about 18,921 (311)

Mechanical Activation of Piezo1 Drives Osteoarthritis Through Kdm5c‐Mediated Epigenetic Silencing

open access: yesAdvanced Science, EarlyView.
Excessive mechanical stress activates Piezo1, triggering Ca2+‐dependent cytoskeletal forces that deform the nucleus and reduce H3K4me3. Kdm5c demethylates H3K4me3 at Col2a1 and Runx3 promoters. Kdm5c knockout rescues degradation. Repurposed telmisartan directly inhibits Kdm5c, blocking this axis and showing disease‐modifying efficacy in mouse OA models
Tianyou Kan   +13 more
wiley   +1 more source

Export Competitiveness of Bulgarian Food and Beverage Industry: Perspectives and Policy Measures

open access: yesИкономика и управление на селското стопанство, 2017
Over the last ten years, the international competitiveness of Bulgaria’s agro-food industry has significantly increased. It is characterized with high export growth, positive trade balance, increase of world market share, and strengthening of the ...
DIANA KOPEVA   +3 more
doaj  

Balancing import and export in development [PDF]

open access: yesGenes & Development, 1999
Affolter, M., Marty, T., Vigano, M. A.
openaire   +3 more sources

Long-Run Growth in Open Economies: Export-Led Cumulative Causation or a Balance-of-Payments Constraint? [PDF]

open access: yes
The post-Keynesian tradition contains two different models of long-run growth in open economies -- the model of export-led cumulative causation (ELCC) originally conceived by Nicholas Kaldor and the model of balance-of-payments-constrained growth (BPCG ...
Robert A. Blecker
core  

Radiation‐Induced Tumor‐Intrinsic LTβR N‐Glycosylation Suppresses Pyroptosis Through TRIM28‐Mediated PCBP2 SUMOylation to Promote Gastric Cancer Radioresistance

open access: yesAdvanced Science, EarlyView.
Radiotherapy triggers LTβR N‐glycosylation, enhancing its overall protein stability and nuclear retention. This accumulation drives TRIM28‐mediated PCBP2 SUMOylation, suppressing pyroptosis and conferring gastric cancer radioresistance. Therapeutically, a targeted nanoplatform (cRGD‐Lipo@EMD) effectively disrupts this regulatory axis, offering a highly
Weijie Zang   +8 more
wiley   +1 more source

An empirical model for the Turkish trade balance: new evidence from ARDL bounds testing analyses [PDF]

open access: yes
In this paper, the determinants of the Turkish trade balance are tried to be analyzed in an empirical modelling approach. For this purpose, the contemporaneous ARDL-based bounds testing has been used to examine the existence of a long run co-integration ...
Korap, Levent
core   +1 more source

Productivity and the Decision to Import and Export: Theory and Evidence [PDF]

open access: yes
This paper develops an open economy model with heterogeneous final goods producers who simultaneously choose whether to export their goods and whether to use imported intermediates. The model highlights mechanisms whereby import policies affect aggregate
Hiroyuki Kasahara, Beverly Lapham
core  

Targeting Lipopolysaccharide Transport Induces Membrane Lipid Remodeling and Sensitizes Acinetobacter baumannii to Colistin Treatment

open access: yesAdvanced Science, EarlyView.
This study identifies C4 as a lead inhibitor of the Lpt system. Notably, C4 potentiates colistin activity by disrupting LPS transport and remodeling phospholipid homeostasis, revealing a functional interplay between the Lpt and Mla systems. These findings establish a mechanistic link between Lpt inhibition and membrane lipid remodeling, positioning Lpt–
Jianya Luo   +6 more
wiley   +1 more source

Newton's Gravity Law and Import Prices in the Asia Pacific [PDF]

open access: yes
exchange rates, import prices, Asia ...
Webber, A.
core  

Assessing Mesoscale Heterogeneities in Hard Carbon Electrodes Through Deep Learning‐Assisted FIB‐SEM Characterization, Manufacturing and Electrochemical Modeling

open access: yesAdvanced Energy Materials, EarlyView.
A combination of discrete and finite element method models for the current collector deformation and electrochemical performance analysis, respectively. The models are calibrated and validated with electrochemical and imaging data of hard carbon electrodes. These electrodes were manufactured with different parameters (slurry solid contents of 35 and 40
Soorya Saravanan   +12 more
wiley   +1 more source

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