Results 61 to 70 of about 31,790 (306)

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

open access: yesAging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang   +3 more
wiley   +1 more source

The Effectiveness of Export Promotion Policies in a General Equilibrium Framework: The Case of the Philippines [PDF]

open access: yes
This study examines the general equilibrium effects of different export promotion policies on imports and production of importables and exportables. Unlike other studies, land as a factor input in the production function has been included.
Boyd, Roy, Doroodian, Khosrow
core   +1 more source

Export promotion agencies revisited [PDF]

open access: yes
The number of national export promotion agencies has tripled over the past two decades. Although more countries made them part of their export strategy, studies criticized their efficacy in developing countries.
Lederman, Daniel   +2 more
core  

Complementarity of Long‐Reads and Optical Mapping in Parkinson's Disease for Structural Variants

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Long‐read sequencing and optical genome mapping technologies have the ability to detect large and complex structural variants. This has led to the discovery of novel pathogenic variants in neurodegenerative movement disorders. Thus, we aimed to systematically compare the SV detection capabilities of OGM and ONT in Parkinson's disease.
André Fienemann   +17 more
wiley   +1 more source

Dundee Discussion Papers in Economics 165:Is monetary discipline a precondition for the effectiveness of Iran’s export promotion policies? [PDF]

open access: yes, 2004
In the last decade, Iranian authorities have implemented a number of trade reforms and export stimulating policies. They have also tried to stabilise the dollar exchange rate and eliminate the black market premium. These policies have had little, if any,
Molana, Hassan, Mozayani, A. H.
core   +1 more source

Unraveling 4‐Phenylbutyrate's Therapeutic Role in SLC6A1 Disorders: Pharmacochaperoning Over HDAC Inhibition

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw   +5 more
wiley   +1 more source

STRATEGIC MANAGEMENT AND IMPROVEMENT OF NATIONAL EXPORT SUPPORT AND PROMOTION SYSTEMS TO ENSURE SUSTAINABLE DEVELOPMENT

open access: yesФінансово-кредитна діяльність: проблеми теорії та практики
The article provides an overview of the main components of national export support and promotion systems. The objective of this article is to substantiate and propose directions and mechanisms for improving the system of support and promotion of ...
Sergey Kudlaenko   +5 more
doaj   +1 more source

MANAGEMENT PROMOTION FOOD EXPORTS - TERMS AND THEORETICAL REFLECTIONS [PDF]

open access: yesScientific Papers Series : Management, Economic Engineering in Agriculture and Rural Development, 2013
The main problem facing businesses today is not the scarcity of goods, but the scarcity of customers. Most entrepreneurs can produce many more goods than consumers are able to buy.
Aurelia LITVIN
doaj  

Export promotion agencies : what works and what doesn't [PDF]

open access: yes
The number of national export promotion agencies (EPAs) has tripled over the past two decades. While more countries have made them part of their national export strategy, studies have criticized their efficiency in developing countries (Hogan, Keesing ...
Lederman, Daniel   +2 more
core  

Formal and Informal Social Care in People With Rheumatic and Musculoskeletal Diseases: A Cross‐Sectional Multicenter Survey

open access: yesArthritis Care &Research, EarlyView.
Objective Rheumatic and musculoskeletal diseases (RMDs) are leading causes of physical disability, necessitating support with activities of daily living. This study describes social care received by patients with RMDs in two disparate regions of England: Salford (urban) and Norfolk (rural).
Mehreen Somro   +6 more
wiley   +1 more source

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