Results 141 to 150 of about 40,637 (278)

A Michaelis‐Arbuzov‐Type Pathway to a Protected 2ʹ‐Deoxy‐2ʹ‐Selenomethyl‐Adenosine‐3ʹ,5ʹ‐Phosphoroselenolate Guanosine Dinucleotide for Use in Modified m7G Cap Synthesis

open access: yesChemistry – A European Journal, EarlyView.
Here we report a synthesis of the dinucleotide 4 for a projected future total synthesis of the m7G cap 1. Highlights of the route include: 1) a 3ʹ‐H‐phosphonate/5ʹ‐selenocyanate Michaelis‐Arbuzov coupling to forge the 3ʹ,5ʹ‐phosphoroselenolate; 2) an Amosova reductive selenomethylation to install the 2ʹ‐SeMe; 3) a solid CPR II 5ʹ‐O‐phosphitylation; and
K. Lawrence E. Hale   +2 more
wiley   +1 more source

Global transcriptomics and targeted metabolite analysis reveal the involvement of the AcrAB efflux pump in physiological functions by exporting signaling molecules in <i>Photorhabdus laumondii</i>. [PDF]

open access: yesMicrobiol Spectr
Hadchity L   +11 more
europepmc   +1 more source

Investigating the Cytoskeleton of DRGs Using Cryo‐Electron Microscopy and Deep Learning

open access: yesCytoskeleton, EarlyView.
ABSTRACT We describe a method for determining the ultrastructural organization of axons and varicosities of cultured dorsal root ganglion (DRG) neurons using cryogenic electron microscopy (cryo‐EM). Cryo‐EM reveals the dimensions, proximity, and overall organization of biological specimens in a near‐native state, avoiding artifacts of fixation and ...
M. Neal Waxham   +3 more
wiley   +1 more source

Quantitative mapping of methionine sensitivity to oxidation in the copper-bound PcuC chaperone. [PDF]

open access: yesRedox Biol
Tarrago L   +10 more
europepmc   +1 more source

Comparative Bioequivalence and Safety Evaluation of Ibuprofen/Phenylephrine Hydrochloride Fixed‐Dose Combination Tablets in Healthy Chinese Volunteers

open access: yesClinical Pharmacology in Drug Development, EarlyView.
Abstract This single‐center, randomized, open‐label bioequivalence program compared two fixed‐dose combination (FDC) tablets containing ibuprofen (200 mg) and phenylephrine hydrochloride (10 mg) from different manufacturers in healthy Chinese adults under fasting and fed conditions. A three‐period, partially replicated crossover design was used for the
Menghan Ye   +8 more
wiley   +1 more source

The impact of temporal hydrogen regulation on hydrogen exporters and their domestic energy transition. [PDF]

open access: yesNat Commun
Schumm L   +6 more
europepmc   +1 more source

Bibliometric Analysis of Technological Innovation in Renewable Energy in the Transport and Logistics Sector

open access: yesCorporate Social Responsibility and Environmental Management, EarlyView.
ABSTRACT This study conducts a comprehensive bibliometric analysis of technological innovation in renewable energy for the transport and logistics sector from 1996 to 2024. Using the Web of Science database, we identify three main research phases and map key collaboration networks and technological trends.
Yui‐yip Lau   +4 more
wiley   +1 more source

Landscape of Research on Accounting Scope 3 Emissions: A Review of Methodologies and Data

open access: yesCorporate Social Responsibility and Environmental Management, EarlyView.
ABSTRACT Scope 3 emissions have been proposed as a critical metric for evaluating corporate carbon footprint, identifying emission sources, and developing mitigation solutions. Yet, widespread corporate reporting of Scope 3 emissions remains limited, highlighting a critical gap in both research and practice.
Zeyu Wang   +3 more
wiley   +1 more source

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