Results 51 to 60 of about 819,643 (245)

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

The role and implications of mammalian cellular circadian entrainment

open access: yesFEBS Letters, EarlyView.
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley   +1 more source

Les boutiques cathares des sites patrimoniaux de l’Aude

open access: yesBelphégor
Le département de l’Aude, avec sa marque « pays cathare », promeut un territoire médiévaliste c’est-à-dire un espace plus ou moins imaginaire ancré dans une histoire médiévale controversée, à partir de ses châteaux mais aussi de ses abbayes et de ses ...
Patrick Fraysse
doaj   +1 more source

Molecular bases of circadian magnesium rhythms across eukaryotes

open access: yesFEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Les Immatériaux : visite de l’exposition au casque

open access: yesHybrid, 2019
Cet article porte sur l’exposition Les Immatériaux organisée en 1985 au Centre Pompidou sous le commissariat général du philosophe Jean-François Lyotard et sous le commissariat de Thierry Chaput, et plus particulièrement sur sa bande sonore.
Marie Vicet
doaj   +1 more source

Biallelic Inactivation of NSD1 Associated With Carcinogenesis in Sotos Syndrome

open access: yes
Pediatric Blood &Cancer, EarlyView.
Nicholas A. Borja   +8 more
wiley   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

open access: yesFEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Le projet Immaterial Art Stock

open access: yesHybrid, 2014
Immaterial Art Stock est un projet de recherche initié en 2012 par deux étudiants-chercheurs, Aurélie Herbet et Frederick Thompson, dans le cadre du laboratoire EN-ER (Espace Numérique-Extension de la Réalité) de l’EnsadLab.
Aurélie Herbet
doaj   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

open access: yesFEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

PENGEMBANGAN BAHAN AJAR DIGITAL INTERAKTIF INTEGRATIF PEMBELAJARAN MENULIS TEKS EKSPOSISI KELAS X SMA [PDF]

open access: yes
The competence of the 21st century in the era of the industrial revolution requires the integration of information and communication technology in the world of education so that the selection of teaching materials must also be adjusted to the demands of ...
Zuhria, Kholilatuz
core  

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