Results 211 to 220 of about 8,026,862 (350)
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Persistent Traumatic Stress Exposure: Rethinking PTSD for Frontline Workers. [PDF]
Cogan N.
europepmc +1 more source
Assessing occupational exposure to sea lamprey pesticides
Diana Ceballos +3 more
openalex +2 more sources
The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli +7 more
wiley +1 more source
Modulatory effects of CeO<sub>2</sub> nanoparticles on bleomycin-induced active pulmonary disease processes in animal and human airway epithelium models. [PDF]
Guo C +8 more
europepmc +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Examining the Relationship Between Adverse Childhood Experiences and ICD-11 Personality Disorder in a Community Mental Health Sample. [PDF]
Martin RC, Sellbom M.
europepmc +1 more source

