Results 21 to 30 of about 1,126,977 (302)

Exposure of Infants to Isoniazid via Breast Milk After Maternal Drug Intake of Recommended Doses Is Clinically Insignificant Irrespective of Metaboliser Status. A Physiologically-Based Pharmacokinetic (PBPK) Modelling Approach to Estimate Drug Exposure of Infants via Breast-Feeding

Frontiers in Pharmacology, 2019
Isoniazid is a first-line anti-tuberculosis drug recommended for treatment of drug-susceptible Mycobacterium tuberculosis infections. Breast-feeding is not contra-indicated while undergoing isoniazid therapy, even though isoniazid was found to migrate ...
Estella Dora Germaine Garessus, Hans Mielke, Ursula Gundert-Remy, Ursula Gundert-Remy, Ursula Gundert-Remy   +4 more
doaj   +1 more source

A mixed-methods community-based participatory research to explore stakeholder’s perspectives and to quantify the effect of crop residue burning on air and human health in Central India: study protocol

BMC Public Health, 2020
Background Crop residue burning adversely affects air quality and consequently human health. India, being one of the largest agro-economies of the world, produces around 500 Million tonnes of crop residue annually most of which is burnt on-farm. However,
Tanwi Trushna, Vishal Diwan, Subroto Shambhu Nandi, Satish Bhagwatrao Aher, Rajnarayan R. Tiwari, Yogesh Damodar Sabde   +5 more
doaj   +1 more source

A framework for expanding aqueous chemistry in the Community Multiscale Air Quality (CMAQ) model version 5.1 [PDF]

Geoscientific Model Development, 2017
This paper describes the development and implementation of an extendable aqueous-phase chemistry option (AQCHEM − KMT(I)) for the Community Multiscale Air Quality (CMAQ) modeling system, version 5.1.
K. M. Fahey, A. G. Carlton, H. O. T. Pye, J. Baek, W. T. Hutzell, C. O. Stanier, K. R. Baker, K. W. Appel, M. Jaoui, J. H. Offenberg   +9 more
doaj   +1 more source

Sourcing data on chemical properties and hazard data from the US-EPA CompTox Chemicals Dashboard: A practical guide for human risk assessment

Environment International, 2021
For the past six decades, human health risk assessment of chemicals has relied on in vivo data from human epidemiological and experimental animal toxicological studies to inform the derivation of non-cancer toxicity values.
Antony J. Williams, Jason C. Lambert, Kris Thayer, Jean-Lou C.M. Dorne   +3 more
doaj   +1 more source

Identifying xenobiotic metabolites with in silico prediction tools and LCMS suspect screening analysis

Frontiers in Toxicology, 2023
Understanding the metabolic fate of a xenobiotic substance can help inform its potential health risks and allow for the identification of signature metabolites associated with exposure.
Matthew Boyce, Kristin A. Favela, Jessica A. Bonzo, Alex Chao, Lucina E. Lizarraga, Laura R. Moody, Elizabeth O. Owens, Grace Patlewicz, Imran Shah, Jon R. Sobus, Russell S. Thomas, Antony J. Williams, Alice Yau, John F. Wambaugh   +13 more
doaj   +1 more source

Degradation of Organophosphorus and Pyrethroid Insecticides in Beverages: Implications for Risk Assessment

Toxics, 2018
Since urinary insecticide metabolites are commonly used as biomarkers of exposure, it is important that we quantify whether insecticides degrade in food and beverages in order to better perform risk assessment.
Samantha A. Radford, Parinya Panuwet, Ronald E. Hunter Jr., Dana Boyd Barr, P. Barry Ryan   +4 more
doaj   +1 more source

Evaluation of health impacts of the improved housing conditions on under-five children in the socioeconomically underprivileged families in central India: A 1-year follow-up study protocol

Frontiers in Public Health, 2022
Unacceptable housing conditions prevalent in Indian urban slums adversely affect the health of residents. The Government of India initiated the Basic Services to the Urban Poor (BSUP) as a sub-mission under the Jawaharlal Nehru National Urban Renewal ...
Yogesh Damodar Sabde, Tanwi Trushna, Uday Kumar Mandal, Vikas Yadav, Devojit Kumar Sarma, Satish Bhagwatrao Aher, Surya Singh, Rajnarayan R. Tiwari, Vishal Diwan   +8 more
doaj   +1 more source

The Residential Population Generator (RPGen): Parameterization of Residential, Demographic, and Physiological Data to Model Intraindividual Exposure, Dose, and Risk

Toxics, 2021
Exposure to chemicals is influenced by associations between the individual’s location and activities as well as demographic and physiological characteristics.
Alexander East, Daniel Dawson, Graham Glen, Kristin Isaacs, Kathie Dionisio, Paul S. Price, Elaine A. Cohen Hubal, Daniel A. Vallero   +7 more
doaj   +1 more source

Are cell phones an indicator of personal exposure to organophosphate flame retardants and plasticizers?

Environment International, 2019
Background: Exposure to organophosphate ester (OPE) flame retardants and plasticizers is widespread and is of concern due to their toxicity. Objectives: To investigate relationships between and within OPE concentrations in air, dust, hands, electronic ...
Congqiao Yang, Shelley A. Harris, Liisa M. Jantunen, Shabana Siddique, Cariton Kubwabo, Dina Tsirlin, Lidija Latifovic, Bruce Fraser, Melissa St-Jean, Regina De La Campa, Hongyu You, Ryan Kulka, Miriam L. Diamond   +12 more
doaj   +1 more source

Risk Categorization of Foods of Non-Animal Origin Subject to United Kingdom Import Controls

Journal of Food Protection
Significant volumes of foods are traded between countries, and this trade brings with it opportunities for foodborne hazards to cross borders and pose a public health risk.
Amy Neill, J.Andrew Hudson, Andy Axon
doaj   +1 more source