Reprotoxins that Should Be Subject to Limit Values for Workerss Exposure
SSRN Electronic Journal, 2016The objective of this project is the identification of substances toxic to reproduction (in short: reprotoxins) which are relevant for workers’ exposure via inhalation at a considerable number of workplaces in Europe and, thus, for which an indicative occupational exposure limit value (IOELV) under the Chemical Agents Directive (CAD) might be suggested.
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N-Methylformamide. Documentation of proposed values of occupational exposure limits (OELs)
Podstawy i Metody Oceny Środowiska Pracy, 2021N-Methylformamide is a colorless liquid with an ammoniacal odor, used as a solvent and an intermediate for chemical reactions. There are no data on occupational exposure in Poland. N-Methylformamide is very well absorbed into the human body. The LD50 values for N-methylformamide administered to animals in various routes are similar (2600 ÷ 4000 mg/kg ...
Elżbieta Bruchajzer +2 more
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Cisplatin. Documentation of proposed values of occupational exposure limits (OELs)
Podstawy i Metody Oceny Środowiska Pracy, 2018Cisplatin is a cytostatic used in the treatment of testicular, ovarian, cervix and bladder cancers, squamous cell carcinoma of a head and a neck, small cell and non-small cell lung cancer. For medical staff, it is available in ampoules of 10 or 50 mg with a concentrate for solution for infusion (1 mg cisplatin/ml).
Anna Pałaszewska-Tkacz +2 more
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[Occupational exposure to wood dust. Health effects and exposure limit values].
Revue d'epidemiologie et de sante publique, 2002This article presents a review of the health effects of occupational exposure to wood dusts and of the data that could be used for setting occupational exposure limits for this nuisance. The causal role of wood dust in the onset of sinonasal cancers is solidly established by numerous epidemiological studies, and the magnitude of the risk is ...
M, Carton, M, Goldberg, D, Luce
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Quinoline. Documentation of proposed values of occupational exposure limits (OELs)
Podstawy i Metody Oceny Środowiska Pracy, 2018Quinoline is a colorless hygroscopic liquid with a pungent odor. It darkens with age. It is soluble in alcohol, ether, benzene and carbon disulfide, and is slightly soluble in water. It is used as a solvent and a decarboxylation reagent, and as a raw material in manufacturing dyes, antiseptics, fungicides, niacins and pharmaceuticals.
Barbara Frydrych +2 more
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Tetrachloroethene. Documentation of proposed values of occupational exposure limits (OELs)
Podstawy i Metody Oceny Środowiska Pracy, 2019etrachloroethene is a colorless, volatile liquid used as a chlorinated solvent in chemical laundries, in metal, machine, aerospace and paint and varnish removers. It is an intermediate for the synthesis of chemical compounds. It has found use as a medium in heat exchangers, in veterinary medicine and for disinfection of grain by fumigation.
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Fluorouracil. Documentation of proposed values of occupational exposure limits (OELs)
Podstawy i Metody Oceny Środowiska Pracy, 2019Fluorouracil is a cytostatic drug used mainly in the treatment of gastrointestinal and skin cancers. It is usually used in a solution, in the form of an intravenous infusion or topically in a cream. The total daily dose of intravenous infusion is usually 12 ÷ 15 mg/kg bw./day, and a maintenance dose of 5 ÷ 10 mg/kg bw.
Małgorzata Kupczewska-Dobecka +1 more
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Application of Pharmacokinetics to Derive Biological Exposure Indexes from Threshold Limit Values
American Industrial Hygiene Association Journal, 1988The importance of incorporating the fundamental concepts of pharmacokinetics into biological monitoring program that involve the collection of various body fluid and tissue specimens is discussed. The application of these principles to establish biological exposures indexes bioequivalent to airborne exposure limits is described.
H W, Leung, D J, Paustenbach
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Trimethylamine. Documentation of proposed values of occupational exposure limits (OELs)
Podstawy i Metody Oceny Środowiska Pracy, 2018Trimethylamine (TMA) is a gas at ambient temperature, which has a pungent, fishy odour. It is commercially available as a compressed gas, 40% aqueous solution or a 33 % solution in ethanol. It is used in organic synthesis, especially of choline salts, as a warning agent for natural gas and flotation agents, in the production of cationic starches ...
Agnieszka Jankowska, Sławomir Czerczak
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Etoposide. Documentation of proposed values of occupational exposure limits (OELs)
Podstawy i Metody Oceny Środowiska Pracy, 2019Etoposide at room temperature is a solid present in the form of a white or yellow-brown crystalline powder. It is an anticancer drug with cytotoxic and anti-mitotic activity, used to treat patients with testicular cancer, acute myelogenous leukemia, lung cancer, non-small-cell lung cancer, adrenal cortex cancer, gastric cancer, hepatoblastoma, acute ...
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