Results 201 to 210 of about 8,398,721 (349)

Antibiofilm activity of a chionodracine‐derived peptide by NMR‐based metabolomics of cell‐free supernatant of Acinetobacter baumannii clinical strains

FEBS Open Bio, EarlyView.
KHS‐Cnd peptide is able to impair biofilm formation and disaggregate mature biofilms in Acinetobacter baumannii clinical isolates. Differences in extracellular metabolites reflect changes in biofilm metabolism due to KHS‐Cnd treatment. Among the differentially represented extracellular metabolites upon KHS‐Cnd treatment, the significantly altered ...
Fernando Porcelli, Enrico Landi, Francesco Maiurano, Irene Paris, Rosanna Papa, Marco Artini, Laura Selan, Stefano Borocci, Francesco Buonocore, Esther Imperlini   +9 more
wiley   +1 more source

Isradipine enhancement of virtual reality cue exposure therapy is effective for individuals with higher baseline cue-induced craving. [PDF]

Drug Alcohol Depend Rep
Papini S, Young CC, Brown RA, Minami H, Morikawa H, Otto MW, Roache JD, Smits JAJ.   +7 more
europepmc   +1 more source

Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276

FEBS Open Bio, EarlyView.
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig, Swanhild Lohse, Sara Elahi, Nils Hartmann, Stefanie Deckert, Shutian Si, Alexander Desuki, Anja Harder   +7 more
wiley   +1 more source

Exposure therapy consortium: Outcomes of the proof-of-principle study. [PDF]

J Anxiety Disord
Smits JAJ, Abramowitz JS, Anderson RA, Arch JJ, Badeja D, Barzilay S, Belanger AN, Borchert T, Bryant E, Burger AS, Dixon LJ, Dutcher CD, Fitzgerald HE, Graham BM, Haberkamp A, Hofmann SG, Hoyer J, Huppert JD, Johnson D, Kabha BQ, Kirk A, Margraf J, McEvoy PM, McSpadden B, Newby J, Otto MW, Papini S, Parsons EM, Pittig A, Pittig R, Rief W, Schaumburg S, Timpano KR, Waltemate L, Wannemüller A, Weise C, Exposure Therapy Consortium.   +36 more
europepmc   +1 more source

SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1

FEBS Open Bio, EarlyView.
Cells expressing SIRT4 (H161Y), a catalytically inactive mutant of the sirtuin SIRT4, fail to upregulate LC3B‐II and exhibit a reduced autophagic flux under stress conditions. Interestingly, SIRT4(H161Y) promotes phosphorylation of ULK1 at S638 and S758 that are associated with inhibition of autophagy initiation.
Isabell Lehmkuhl, Khawar Amin, Lydia Gabriel, Nils Hampel, Afshin Iram, Julia Hesse, Constanze Wiek, Jasmin Thuy Vy Nguyen, Helmut Hanenberg, Jürgen Scheller, M. Reza Ahmadian, Björn Stork, Doreen M. Floss, Roland P. Piekorz   +13 more
wiley   +1 more source

Virtual reality-based cue exposure therapy reduces psychological craving in men with methamphetamine use disorder: a randomized controlled trial. [PDF]

Transl Psychiatry
Huang Q, Chen X, Wang X, Tang Y, Wang W, Chao L, Nie Y, Peng S, Zhao L, Shen H, Liao Z.   +10 more
europepmc   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

Combining Ketamine Infusions and Written Exposure Therapy for Chronic PTSD: An Open-Label Trial. [PDF]

J Clin Psychiatry
Feder A, Brown O, Rutter SB, Cahn L, Overbey JR, Seeley SH, Yu A, Bonanno PA, Fremont RA, Delgado AA, Jha MK, Costi S, Yehuda R, Schiller D, Pietrzak RH, Charney DS, Sloan DM, Murrough JW.   +17 more
europepmc   +1 more source

Narrative Exposure Therapy (KIDNET) [PDF]

Word of Mouth, 2020
openaire   +1 more source

Automated virtual reality exposure therapy for spider phobia vs. in-vivo one-session treatment: A randomized non-inferiority trial.

Behaviour Research and Therapy, 2019
A. Miloff, P. Lindner, Peter Dafgård, Stefan Deak, M. Garke, William Hamilton, Julia Heinsoo, Glenn Kristoffersson, Jonas Rafi, Kerstin Sindemark, Jessica Sjölund, Maria Zenger, Lena Reuterskiöld, G. Andersson, P. Carlbring   +14 more
semanticscholar   +1 more source