Results 201 to 210 of about 1,815,249 (352)

A SemimechanisticOcular Pharmacokinetic Model forADVM-022 Gene Therapy Describing the Dose-Exposure Relationship inMonkeys and the Scaling to Human

Florian Hugi (21754829), Jannik Vollmer (9454680), Lionel Renaud (21754832), Matthias Machacek (9454683)   +3 more
openalex   +1 more source

Exposure therapy consortium: Outcomes of the proof-of-principle study. [PDF]

J Anxiety Disord
Smits JAJ, Abramowitz JS, Anderson RA, Arch JJ, Badeja D, Barzilay S, Belanger AN, Borchert T, Bryant E, Burger AS, Dixon LJ, Dutcher CD, Fitzgerald HE, Graham BM, Haberkamp A, Hofmann SG, Hoyer J, Huppert JD, Johnson D, Kabha BQ, Kirk A, Margraf J, McEvoy PM, McSpadden B, Newby J, Otto MW, Papini S, Parsons EM, Pittig A, Pittig R, Rief W, Schaumburg S, Timpano KR, Waltemate L, Wannemüller A, Weise C, Exposure Therapy Consortium.   +36 more
europepmc   +1 more source

The effect of salubrinal on the endoplasmic reticulum stress pathway in heat‐stressed spermatogonial cells in vitro

FEBS Open Bio, EarlyView.
This study investigates the protective role of salubrinal against heat‐induced endoplasmic reticulum (ER) stress in mouse spermatogenic cells (GC1 and GC2). By modulating the ER stress pathway, salubrinal alleviates cellular stress and supports spermatogenic cell survival, suggesting its potential as a therapeutic candidate for heat‐related infertility.
Suna Karadeniz Saygili, Mustafa Oztatlici, Mahmut Kemal Ozbilgin   +2 more
wiley   +1 more source

Monoclonal antibody therapy protects nonhuman primates against mucosal exposure to Lassa virus [PDF]

Robert W. Cross, Karla A. Fenton, Courtney Woolsey, Abhishek N. Prasad, Viktoriya Borisevich, Krystle N. Agans, Daniel J. Deer, Natalie S. Dobias, Alyssa C. Fears, Megan L. Heinrich, Joan B. Geisbert, Robert F. Garry, Luis M. Branco, Thomas W. Geisbert   +13 more
openalex   +1 more source

Multiple haematological malignancies in a patient with rheumatoid arthritis without exposure to disease modifying therapy [PDF]

, 2006
H. Piper, D Mulherin, N Hardwick
openalex   +1 more source

Virtual reality-based cue exposure therapy reduces psychological craving in men with methamphetamine use disorder: a randomized controlled trial. [PDF]

Transl Psychiatry
Huang Q, Chen X, Wang X, Tang Y, Wang W, Chao L, Nie Y, Peng S, Zhao L, Shen H, Liao Z.   +10 more
europepmc   +1 more source

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

FEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies, Garth L. Maker, Ian F. Musgrave, Samantha Lodge   +3 more
wiley   +1 more source

Childhood neglects: intimate partner violence in PTSD-SUD comorbid patients treated with narrative exposure therapy. [PDF]

Eur J Psychotraumatol
Nolasco Ferreira V, Vigfusdottir J, Breivik E, Jonsbu E, Bell-Mizori AR, Domogalla SA, Tokovska M.   +6 more
europepmc   +1 more source

Anticancer sensitivities and biological characteristics of HCT116 cells resistant to the selective poly(ADP‐ribose) glycohydrolase inhibitor

FEBS Open Bio, EarlyView.
We analyzed alterations of PAR metabolism‐related proteins in PARG inhibitor‐resistant HCT116RPDD cells. Although PARG levels remained unchanged, HCT116RPDD cells exhibited reduced PARP1 and ARH3 expression and elevated PAR levels. Interestingly, HCT116RPDD cells exhibited slightly elevated intracellular NAD+/NADH and ATP levels. Our findings suggest a
Kaede Tsuda, Yoko Ogino, Akira Sato
wiley   +1 more source

Gamified Virtual Reality Exposure Therapy for Mysophobia: Evaluating the Efficacy of a Simulated Sneeze Intervention [PDF]

Md Mosharaf Hossan, Rifat Ara Tasnim, Farjana Z. Eishita   +2 more
openalex   +1 more source