Results 41 to 50 of about 1,028,562 (262)

La thérapie d’exposition en réalité virtuelle en France

open access: yesRevue d'anthropologie des connaissances
This article analyses the development of virtual reality exposure therapy (VRET) in French psychiatry as a perpetually emerging innovation. Since the late 1990s, VRET has periodically emerged and disappeared in various hospital departments without ...
Elsa Forner, Céline Borelle
doaj   +1 more source

Clinical Virtual Reality tools to advance the prevention, assessment, and treatment of PTSD

open access: yesEuropean Journal of Psychotraumatology, 2017
Numerous reports indicate that the incidence of posttraumatic stress disorder (PTSD) in Operation Enduring Freedom/Operation Iraqi Freedom/Operation New Dawn (OEF/OIF/OND) military personnel has created a significant behavioural healthcare challenge ...
Albert ‘Skip’ Rizzo   +1 more
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Reflections on the 10th World Congress of Cognitive and Behavioural Therapies: Lessons for African occupational therapists

open access: yesSouth African Journal of Occupational Therapy
Cognitive behavioural therapy (CBT) is a well-researched and evidence-based psychotherapy that is underutilised in Africa. CBT presents opportunities for occupational therapists to expand their practice, for example by promoting engagement in meaningful
Nicola Ann Plastow   +2 more
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Maximizing expectancy violation and exposure outcomes in patients with PTSD

open access: yesEuropean Journal of Psychotraumatology
Background: It has been proposed that maximizing expectancy violation enhances the efficacy of exposure therapy. The clinical utility of expectancy violation remains unclear and it has not yet been studied in PTSD.Objective: We aimed to test whether ...
Marike J. Kooistra   +4 more
doaj   +1 more source

Inferiority or Even Superiority of Virtual Reality Exposure Therapy in Phobias?—A Systematic Review and Quantitative Meta-Analysis on Randomized Controlled Trials Specifically Comparing the Efficacy of Virtual Reality Exposure to Gold Standard in vivo Exposure in Agoraphobia, Specific Phobia, and Social Phobia

open access: yesFrontiers in Psychology, 2019
Background: Convincing evidence on Virtual Reality (VR) exposure for phobic anxiety disorders has been reported, however, the benchmark and golden standard for phobia treatment is in vivo exposure.
Theresa F. Wechsler   +2 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Disgusted, but amused: positive emotion attenuates disgust elicited by film clips

open access: yesFrontiers in Psychology
BackgroundDisorders like obsessive-compulsive disorder are associated with heightened disgust. Research suggests that dominant methods for treating such disorders (e.g., exposure therapies) are less effective at targeting disgust.
Benjamin J. Mitchell, Karin G. Coifman
doaj   +1 more source

Efficacy of inhibitory learning theory-based exposure and response prevention and selective serotonin reuptake inhibitor in obsessive-compulsive disorder management: A treatment comparison

open access: yesIndustrial Psychiatry Journal, 2018
Background: The majority of treatment research on obsessive-compulsive disorder (OCD) has focused on emotional processing theory (EPT)-based exposure-based interventions.
Narendra Nath Samantaray   +2 more
doaj   +1 more source

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