Results 171 to 180 of about 422,721 (317)
Arthritis Care &Research, EarlyView.Objective Hydroxychloroquine (HCQ) is a cornerstone therapy in systemic lupus erythematosus (SLE), but the weight‐based dosing does not account for clinical factors that can introduce individual variability in drug metabolism and clearance. We leveraged longitudinal data from a prospective SLE cohort to identify clinical factors that predict ...
Jay J. Patel +6 more
wiley +1 more source
The Human Exposome: Integrating the Environment, Human Health, and Society for the Next 60 years. [PDF]
Environ Sci TechnolGago-Ferrero P +7 more
europepmc +1 more source
Arthritis Care &Research, EarlyView.Objective The aim of this study was to determine the differences in demographic, serologic, and clinical characteristics between male and female patients with systemic sclerosis (SSc) in an Australian cohort. Methods This was a retrospective observational study using data from the Australian Scleroderma Cohort Study.
Emily Lin +14 more
wiley +1 more source
Arthritis Care &Research, EarlyView.Objective The concern that nonsteroidal anti‐inflammatory drugs (NSAIDs) may precipitate flares of inflammatory bowel disease (IBD) has limited their use in managing musculoskeletal symptoms in those with IBD, but safety data are mixed. Methods This retrospective cohort study included patients with IBD aged at least 18 years from Optum's deidentified ...
Adam S. Mayer +4 more
wiley +1 more source
Precision phenotyping of elevated arousal in posttraumatic stress disorder: implications for personalized GABAergic pharmacotherapy. [PDF]
Front PsychiatryVasquez VR, Howlett JR.
europepmc +1 more source
Arthritis Care &Research, EarlyView.Objective This study aimed to describe real‐world trends in preconception and prenatal use of antirheumatic drugs among pregnant individuals with rheumatic diseases in Ontario, Canada. Methods We conducted a time‐series analysis using repeated cross‐sectional data to examine annual patterns of disease‐modifying antirheumatic drug (DMARD) use among ...
Shenthuraan Tharmarajah +6 more
wiley +1 more source
Differential Impact of Pharmacokinetic and Pharmacodynamic Variability on Response to Combination Therapy. [PDF]
Pharmacol Res PerspectBisaso KR +3 more
europepmc +1 more source
Arthritis Care &Research, EarlyView.Objective To investigate the association between rheumatoid arthritis (RA) and coronary artery calcium (CAC) prevalence, incidence, and progression over four years in adults without prior cardiovascular disease. Methods A case‐cohort study within the Brazilian Longitudinal Study of Adult Health (ELSA‐Brasil) included 585 participants (86 patients with ...
Patrícia Fonseca Estrada +7 more
wiley +1 more source
Citronellol-functionalized natural silica: a biogenic approach for antifungal and antibacterial material applications [PDF]
Introduction: New bioactive hybrid materials to prevent biofilm-induced biodeterioration are a significant challenge in indoor environments, where contaminants from microbial films compromise structural integrity and contribute to air pollution, posing ...
Barberia Roque, Leyanet +4 more
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Accompanied management and evaluation method of exposure risks to biological agents.
, 2017 The presence of biological agents in the workplace may result in hazardous situations for workers. The present study was carried out in the microbiology laboratory of a Medical School and the methodology was based on the qualitative method presented in the Technical Note of Spanish Prevention (NTP 833) and the Accompanied Method of Biological Risk ...
Veiga, Rui +2 more
openaire +1 more source