Results 1 to 10 of about 517 (104)
Superexpressão Gênica PTEN em Tecidos Miocárdicos de Pacientes de Cirurgia de Revascularização Miocárdica [PDF]
Arquivos Brasileiros de Cardiologia, 2023 Resumo Fundamento: A doença arterial coronariana é um distúrbio complexo que causa morte em todo o mundo. Um dos genes envolvidos no desenvolvimento dessa doença pode ser o PTEN. Objetivos: Nosso objetivo foi investigar a expressão gênica e proteica do
Reyhan Tahtasakal +8 more
doaj +3 more sources
Efeitos do Exercício Aeróbico Tardio na Remodelação Cardíaca de Ratos com Infarto do Miocárdio Pequeno [PDF]
Arquivos Brasileiros de Cardiologia, 2021 Resumo Fundamento: O exercício físico tem sido considerado uma importante terapia não farmacológica para a prevenção e tratamento das doenças cardiovasculares. No entanto, seus efeitos na remodelação cardíaca leve não são claros.
Lidiane M. Souza +12 more
doaj +4 more sources
Characterization of the RNA-Binding Protein TcSgn1 in Trypanosoma cruzi
Microorganisms, 2021 RNA-binding proteins (RBPs) participate in several steps of post-transcriptional regulation of gene expression, such as splicing, messenger RNA transport, mRNA localization, and translation.
Camila Oliveira +3 more
doaj +1 more source
Modulation of Virulence Factors during Trypanosoma cruzi Differentiation
Pathogens, 2022 Chagas disease is a neglected tropical disease caused by Trypanosoma cruzi. This protozoan developed several mechanisms to infect, propagate, and survive in different hosts.
Camila Oliveira +3 more
doaj +1 more source
Cell Communication and Signaling, 2021 Background Androgen receptor (AR) and polycomb repressive complex 2 (PRC2) are known to co-occupy the loci of genes that are downregulated by androgen-stimulus. Long intergenic non-coding RNA (lincRNA) PVT1 is an overexpressed oncogene that is associated
Alexandre Videira +3 more
doaj +1 more source
Life, 2023 Our aim was to carry out a qualitative and quantitative synthesis of the influence of CCR5 genetic variants on Chagas disease (CD) through a systematic review. A total of 1197 articles were analyzed, and eleven were included in the review.
Jean Moisés Ferreira +6 more
doaj +1 more source
Guidelines for the purification and characterization of extracellular vesicles of parasites
Journal of Extracellular Biology, Volume 2, Issue 10, October 2023., 2023 Abstract Parasites are responsible for the most neglected tropical diseases, affecting over a billion people worldwide (WHO, 2015) and accounting for billions of cases a year and responsible for several millions of deaths. Research on extracellular vesicles (EVs) has increased in recent years and demonstrated that EVs shed by pathogenic parasites ...
Carmen Fernandez‐Becerra +30 more
wiley +1 more source
Veterinary Dermatology, Volume 32, Issue 4, Page 331-e92, August 2021., 2021 Background MicroRNAs (miRNA) are short, single‐stranded RNA molecules that regulate gene expression in a post‐transcriptional manner. Their expression is proposed to be tissue‐specific and alterations in miRNA expression have been detected in many diseases. Objective To compare miRNA expression in the skin of healthy Labrador and golden retrievers, and
Marie Isabel Morlang +3 more
wiley +1 more source
Drosophila melanogaster: A Powerful Tiny Animal Model for the Study of Metabolic Hepatic Diseases
Frontiers in Physiology, 2021 Animal experimentation is limited by unethical procedures, time-consuming protocols, and high cost. Thus, the development of innovative approaches for disease treatment based on alternative models in a fast, safe, and economic manner is an important, yet
Karen C. M. Moraes, Jacques Montagne
doaj +1 more source
Non-Coding RNA, 2020 Schistosoma japonicum is a flatworm that causes schistosomiasis, a neglected tropical disease. S. japonicum RNA-Seq analyses has been previously reported in the literature on females and males obtained during sexual maturation from 14 to 28 days post ...
Lucas F. Maciel +2 more
doaj +1 more source