BMC Genomics, 2008 BackgroundThe bite of spiders belonging to the genus Loxosceles can induce a variety of clinical symptoms, including dermonecrosis, thrombosis, vascular leakage, haemolysis, and persistent inflammation.
M. F. Fernandes-Pedrosa +6 more
semanticscholar +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Gene expression profiling of coelomic cells and discovery of immune-related genes in the earthworm, Eisenia andrei, using expressed sequence tags [PDF]
, 2014 Eun Sik Tak +2 more
openalex +2 more sources
In Silico Investigation of Conserved miRNAs and Their Targets From the Expressed Sequence Tags in Neospora Caninum Genome. [PDF]
Bioinform Biol Insights, 2021 Das M +9 more
europepmc +1 more source
Aspect-Based Sentiment Analysis Using a Two-Step Neural Network Architecture
, 2017 The World Wide Web holds a wealth of information in the form of unstructured texts such as customer reviews for products, events and more. By extracting and analyzing the expressed opinions in customer reviews in a fine-grained way, valuable ...
AP Aprosio +7 more
core +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Expressed sequence tags from life cycle stages of Trichinella spiralis: Application to biology and parasite control [PDF]
, 2005 While the approach taken to date to study Trichinella spp., involves mainly characterization of individual genes of interest, we initiated a genomics approach as an antecedent to more complete genome sequencing.
Appleton, Judith +3 more
core
Does an expressed sequence tag (EST) library ofSalsola iberica(tumbleweed) help to understand plant responses to environmental stresses? [PDF]
, 2010 Sam R. Zwenger +2 more
openalex +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Analysis of expressed sequence tags generated from full-length enriched cDNA libraries of melon
BMC Genomics, 2011 Background Melon (Cucumis melo), an economically important vegetable crop, belongs to the Cucurbitaceae family which includes several other important crops such as watermelon, cucumber, and pumpkin.
Bendahmane Abdelhafid +17 more
doaj +1 more source