Results 11 to 20 of about 28,109,296 (301)

Pathway expression analysis

Scientific Reports, 2022
AbstractThis paper introduces a pathway expression framework as an approach for constructing derived biomarkers. The pathway expression framework incorporates the biological connections of genes leading to a biologically relevant model. Using this framework, we distinguish between shedding subjects post-infection and all subjects pre-infection in human
Nathan Mankovich, Eric Kehoe, Amy Peterson, Michael Kirby   +3 more
openaire   +3 more sources

Characterization of RNA in exosomes secreted by human breast cancer cell lines using next-generation sequencing [PDF]

PeerJ, 2013
Exosomes are nanosized (30–100 nm) membrane vesicles secreted by most cell types. Exosomes have been found to contain various RNA species including miRNA, mRNA and long non-protein coding RNAs. A number of cancer cells produce elevated levels of exosomes.
Piroon Jenjaroenpun, Yuliya Kremenska, Vrundha M. Nair, Maksym Kremenskoy, Baby Joseph, Igor V. Kurochkin   +5 more
doaj   +2 more sources

BRMS1 in Gliomas—An Expression Analysis

Cancers, 2023
The metastatic suppressor BRMS1 interacts with critical steps of the metastatic cascade in many cancer entities. As gliomas rarely metastasize, BRMS1 has mainly been neglected in glioma research. However, its interaction partners, such as NFκB, VEGF, or MMPs, are old acquaintances in neurooncology.
Jonas Feldheim, Almuth F. Kessler, Julia J. Feldheim, Dominik Schmitt, Christoph Oster, Lazaros Lazaridis, Martin Glas, Ralf-Ingo Ernestus, Camelia M. Monoranu, Mario Löhr, Carsten Hagemann   +10 more
openaire   +4 more sources

Virtual tissue expression analysis

Bioinformatics, 2023
Abstract Motivation Bulk RNA expression data are widely accessible, whereas single-cell data are relatively scarce in comparison. However, single-cell data offer profound insights into the cellular composition of tissues and cell type-specific gene regulation, both of which remain hidden in ...
Simeth, Jakob, Hüttl, Paul, Schön, Marian, Nozari, Zahra, Huttner, Michael, Schmidt, Tobias, Altenbuchinger, Michael, Spang, Rainer, Mathelier, Anthony   +8 more
openaire   +4 more sources

Genome-wide identification and expression analysis of GDP-D-mannose pyrophosphorylase and KATANIN in Corymbia citriodora

Frontiers in Plant Science, 2023
The GDP-D-mannose pyrophosphorylase (GMP) and microtubule severing enzyme KATANIN (KTN) are crucial for wood formation. Although functional identification has been performed in Arabidopsis, few comprehensive studies have been conducted in forest trees ...
Chubiao Wang, Jianzhong Luo, Wenliang He, Anying Huang, Wanhong Lu, Yan Lin, Yuduan Ou   +6 more
doaj   +1 more source

High-throughput toxicogenomic screening of chemicals in the environment using metabolically competent hepatic cell cultures

npj Systems Biology and Applications, 2021
The ToxCast in vitro screening program has provided concentration-response bioactivity data across more than a thousand assay endpoints for thousands of chemicals found in our environment and commerce.
Jill A. Franzosa, Jessica A. Bonzo, John Jack, Nancy C. Baker, Parth Kothiya, Rafal P. Witek, Patrick Hurban, Stephen Siferd, Susan Hester, Imran Shah, Stephen S. Ferguson, Keith A. Houck, John F. Wambaugh   +12 more
doaj   +1 more source

Genome-Wide Identification of Callose Synthase Family Genes and Their Expression Analysis in Floral Bud Development and Hormonal Responses in Prunus mume

Plants, 2023
Callose is an important polysaccharide composed of beta-1,3-glucans and is widely implicated in plant development and defense responses. Callose synthesis is mainly catalyzed by a family of callose synthases, also known as glucan synthase-like (GSL ...
Man Zhang, Wenhui Cheng, Jia Wang, Tangren Cheng, Xinlian Lin, Qixiang Zhang, Cuiling Li   +6 more
doaj   +1 more source

Phylogenetic Analysis of Gene Expression [PDF]

Integrative and Comparative Biology, 2013
14 pages, 4 ...
Dunn, Casey W., Luo, Xi, Wu, Zhijin
openaire   +3 more sources

Identification of common oncogenic and early developmental pathways in the ovarian carcinomas controlling by distinct prognostically significant microRNA subsets

BMC Genomics, 2017
Background High-grade serous ovarian carcinoma (HG-SOC) is the dominant tumor histologic type in epithelial ovarian cancers, exhibiting highly aberrant microRNA expression profiles and diverse pathways that collectively determine the disease ...
Vladimir A. Kuznetsov, Zhiqun Tang, Anna V. Ivshina   +2 more
doaj   +1 more source

A systems biology design and implementation of novel bioinformatics software tools for high throughput gene expression analysis [PDF]

, 2009
This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.Microarray technology has revolutionized the field of molecular biology by offering an efficient and cost effective platform for the simultaneous ...
Khan, Mohsin Amir Faiz
core   +7 more sources