Results 171 to 180 of about 2,116,656 (327)

Novel oncogene 5MP1 reprograms c-Myc translation initiation to drive malignant phenotypes in colorectal cancerResearch in context

EBioMedicine, 2019
Background: Translational reprogramming through controlled initiation from non-AUG start codons is considered a crucial driving force in tumorigenesis and tumor progression.
Kuniaki Sato, Takaaki Masuda, Qingjiang Hu, Taro Tobo, Sarah Gillaspie, Atsushi Niida, Mackenzie Thornton, Yousuke Kuroda, Hidetoshi Eguchi, Takashi Nakagawa, Katsura Asano, Koshi Mimori   +11 more
doaj  

Cell‐free DNA aneuploidy score as a dynamic early response marker in prostate cancer

Molecular Oncology, EarlyView.
mFast‐SeqS‐based genome‐wide aneuploidy scores are concordant with aneuploidy scores obtained by whole genome sequencing from tumor tissue and can predict response to ARSI treatment at baseline and, at an early time point, to ARSI and taxanes. This assay can be easily performed at low cost and requires little input of cfDNA. Cell‐free circulating tumor
Khrystany T. Isebia, Anouk C. de Jong, Lisanne F. van Dessel, Vanja de Weerd, Corine Beaufort, Jean Helmijr, José Alberto Nakauma‐González, Job van Riet, Paul Hamberg, Daniel Vis, Michiel S. van der Heijden, Nick Beije, Martijn P. Lolkema, Teoman Deger, Saskia M. Wilting, Ronald de Wit, Maurice P. H. M. Jansen, John W. M. Martens   +17 more
wiley   +1 more source

Establishment of cancer/testis antigen profiling based on clinicopathological characteristics in resected pathological stage III non-small cell lung cancer

Cancer Management and Research, 2018
Shi Jin,1,* Shoubo Cao,1,2,* Aleksei Grigorev,3,* Jianhua Li,4 Qingwei Meng,1 Chunyan Wang,1,2 Meiyan Feng,5 Jing Hu,1 Feng Jiang,3 Yan Yu1 1Department of Medical Oncology, Harbin Medical University Cancer Hospital, Harbin, People’s Republic of ...
Jin S, Cao S, Grigorev A, Li J, Meng Q, Wang C, Feng M, Hu J, Jiang F, Yu Y   +9 more
doaj  

Integration of single‐cell and bulk RNA‐sequencing data reveals the prognostic potential of epithelial gene markers for prostate cancer

Molecular Oncology, EarlyView.
Prostate cancer is a leading malignancy with significant clinical heterogeneity in men. An 11‐gene signature derived from dysregulated epithelial cell markers effectively predicted biochemical recurrence‐free survival in patients who underwent radical surgery or radiotherapy.
Zhuofan Mou, Lorna W. Harries
wiley   +1 more source

Author Correction: Design and TCAD analysis of few-layer graphene/ZnO nanowires heterojunction-based photodetector in UV spectral region. [PDF]

Sci Rep
Bansal S, Kumar S, Jain A, Rohilla V, Prakash K, Gupta A, Ali T, Alenezi AM, Islam MS, Soliman MS, Islam MT.   +10 more
europepmc   +1 more source

Clinical significance of stratifying prostate cancer patients through specific circulating genes

Molecular Oncology, EarlyView.
We tested a specific panel of genes representative of luminal, neuroendocrine and stem‐like cells in the blood of prostate cancer patients, showing predictive value from diagnosis to late stages of disease. This approach allows monitoring of treatment responses and outcomes at specific time points in trajectories.
Seta Derderian, Edouard Jarry, Arynne Santos, Quentin Vesval, Lucie Hamel, Rafael Sanchez‐Salas, Alexis Rompré‐Brodeur, Wassim Kassouf, Raghu Rajan, Fadi Brimo, Marie Duclos, Armen Aprikian, Simone Chevalier   +12 more
wiley   +1 more source

Detection of human emotions through facial expressions using hybrid convolutional neural network-recurrent neural network algorithm

Intelligent Systems with Applications
Cognitive science plays a pivotal role in deciphering human behavior by understanding and interpreting emotions prevalent in everyday life. These emotions manifest through various cues, including speech patterns, body language, and notably, facial ...
Haposan Vincentius Manalu, Achmad Pratama Rifai   +1 more
doaj  

scPEDSSC: proximity enhanced deep sparse subspace clustering method for scRNA-seq data. [PDF]

PLoS Comput Biol
Wei X, Wu J, Li G, Liu J, Wu X, He C.
europepmc   +1 more source

MET variants with activating N‐lobe mutations identified in hereditary papillary renal cell carcinomas still require ligand stimulation

Molecular Oncology, EarlyView.
MET variants in the N‐lobe of the kinase domain, found in hereditary papillary renal cell carcinoma, require ligand stimulation to promote cell transformation, in contrast to other RTK variants. This suggests that HGF expression in the microenvironment is important for tumor growth in such patients. Their sensitivity to MET inhibitors opens the way for
Célia Guérin, Audrey Vinchent, Marie Fernandes, Isabelle Damour, Agathe Laratte, Rémi Tellier, Gabriella O. Estevam, Jean‐Pascal Meneboo, Céline Villenet, Clotilde Descarpentries, James S. Fraser, Martin Figeac, Alexis B. Cortot, Etienne Rouleau, David Tulasne   +14 more
wiley   +1 more source

Real-time fear emotion recognition in mice based on multimodal data fusion. [PDF]

Sci Rep
Wang H, Shi Z, Hu R, Wang X, Chen J, Che H.   +5 more
europepmc   +1 more source