Results 51 to 60 of about 1,325,838 (268)
OSG-GEM: Gene Expression Matrix Construction Using the Open Science Grid
Bioinformatics and Biology Insights, 2016 High-throughput DNA sequencing technology has revolutionized the study of gene expression while introducing significant computational challenges for biologists.
William L. Poehlman +4 more
doaj +1 more source
Towards a New Virtualist Design Research Programme
FORMakademisk, 2013 This paper considers how the influence of computer-cyber networks informs a new way of seeing on the part of designers as well as design researchers. In an adaptation of the notion of “virtual realities” made possible by computer technology, this new ...
David Wang
doaj +1 more source
IEEE Access, 2023 Mental fatigue is a psychophysical condition with a significant adverse effect on daily life, compromising both physical and mental wellness. We are experiencing challenges in this fast-changing environment, and mental fatigue problems are becoming more ...
Hamwira Yaacob +5 more
doaj +1 more source
FEBS Letters, EarlyView.Atovaquone is an antimalarial requiring potentiation for sufficient efficacy. We pursued strategies to enhance its activity, showing that 4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase, decreasing ubiquinone biosynthesis. Since atovaquone competes with ubiquinol in mitochondria, 4‐nitrobenzoate facilitates its action, potentiating ...
Ignasi Bofill Verdaguer +7 more
wiley +1 more source
Learning Causal Biological Networks With the Principle of Mendelian Randomization
Frontiers in Genetics, 2019 Although large amounts of genomic data are available, it remains a challenge to reliably infer causal (i. e., regulatory) relationships among molecular phenotypes (such as gene expression), especially when multiple phenotypes are involved.
Md. Bahadur Badsha, Audrey Qiuyan Fu
doaj +1 more source
Evolutionary Computation in High Energy Physics [PDF]
, 2008 Evolutionary Computation is a branch of computer science with which, traditionally, High Energy Physics has fewer connections. Its methods were investigated in this field, mainly for data analysis tasks. These methods and studies are, however, less known
Teodorescu, Liliana
core +2 more sources
FEBS Letters, EarlyView.Cells must clear mislocalized or faulty proteins from membranes to survive. The AAA+ ATPase Msp1 performs this task, but dissecting how its six subunits work together is challenging. We engineered linked dimers with varied numbers of functional subunits to reveal how Msp1 subunits cooperate and use energy to extract proteins from the lipid bilayer ...
Deepika Gaur +5 more
wiley +1 more source
Sex chromosome evolution in parasitic nematodes of humans
Nature Communications, 2020 Many nematode worms, including Caenorhabditis elegans have XX/XO sex determination, while other species have XY. The authors use a new genome assembly of the filarial parasite Brugia malayi and published data to show that nematode sex chromosome ...
Jeremy M. Foster +22 more
doaj +1 more source
Digital Art, Interactive Animation and Creative Expression in the Computer Science Curriculum [PDF]
, 2022 Sandra Woolley +3 more
openalex +1 more source
Computer algebra tools for Feynman integrals and related multi-sums [PDF]
, 2018 In perturbative calculations, e.g., in the setting of Quantum Chromodynamics (QCD) one aims at the evaluation of Feynman integrals. Here one is often faced with the problem to simplify multiple nested integrals or sums to expressions in terms of ...
Blümlein, Johannes, Schneider, Carsten
core +2 more sources