occumb: An R package for site occupancy modeling of eDNA metabarcoding data
This study introduces a new R package, occumb, for the convenient application of site occupancy modeling using environmental DNA (eDNA) metabarcoding data. We outline a data analysis workflow, including data setup, model fitting, model assessment, and comparison of potential study settings based on model predictions, all of which can be performed using
Keiichi Fukaya, Yuta Hasebe
wiley +1 more source
Towards a New Virtualist Design Research Programme
This paper considers how the influence of computer-cyber networks informs a new way of seeing on the part of designers as well as design researchers. In an adaptation of the notion of “virtual realities” made possible by computer technology, this new ...
David Wang
doaj +1 more source
Anti-Adjacency Matrices of Certain Graphs Derived from Some Graph Operations
If we go through the literature, one can find many matrices that are derived for a given simple graph. The one among them is the anti-adjacency matrix which is given as follows; The anti-adjacency matrix of a simple undirected graph $G$ with vertex set
Manju V N, Athul T B, Suresh Singh G
doaj +1 more source
Dendritic cells steering antigen and leukocyte traffic in lymph nodes
Dendritic cells are key players in the activation of T cells and their commitment to effector function. In this In a Nutshell Review, we will discuss how dendritic cells guide the trafficking of antigen and leukocytes in the lymph node, thus influencing T‐cell activation processes. Dendritic cells (DCs) play a central role in initiating and shaping the
Enrico Dotta+3 more
wiley +1 more source
FoxO1 signaling in B cell malignancies and its therapeutic targeting
FoxO1 has context‐specific tumor suppressor or oncogenic character in myeloid and B cell malignancies. This includes tumor‐promoting properties such as stemness maintenance and DNA damage tolerance in acute leukemias, or regulation of cell proliferation and survival, or migration in mature B cell malignancies.
Krystof Hlavac+3 more
wiley +1 more source
Learning to communicate computationally with Flip: a bi-modal programming language for game creation [PDF]
Teaching basic computational concepts and skills to school children is currently a curricular focus in many countries. Running parallel to this trend are advances in programming environments and teaching methods which aim to make computer science more ...
Basawapatna+56 more
core +1 more source
Learning Causal Biological Networks With the Principle of Mendelian Randomization
Although large amounts of genomic data are available, it remains a challenge to reliably infer causal (i. e., regulatory) relationships among molecular phenotypes (such as gene expression), especially when multiple phenotypes are involved.
Md. Bahadur Badsha, Audrey Qiuyan Fu
doaj +1 more source
Computational identification of protein-coding sequences by comparative analysis [PDF]
Gene prediction is an essential step in understanding the genome of a species once it has been sequenced. For that, a promising direction in current research on gene finding is a comparative genomics approach. In this paper, we present a novel approach to identifying evolutionarily conserved protein-coding sequences in genomes.
Wu, Feihong+3 more
openaire +18 more sources
Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia
This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley +1 more source
OPPORTUNITIES OF FLOW CYTOMETRY IN DIAGNOSTICS OF INFECTIOUS DISEASES. PART 1
. Development of a modern medical science demands more thorough and deeper approach to diagnostics of diseases. New diagnostic technologies for these investigations are necessary and flow cytometry is such technology.
S. V. Khaidukov, A. V. Zurochka
doaj +1 more source