Results 61 to 70 of about 1,344,767 (284)

Learning Causal Biological Networks With the Principle of Mendelian Randomization

Frontiers in Genetics, 2019
Although large amounts of genomic data are available, it remains a challenge to reliably infer causal (i. e., regulatory) relationships among molecular phenotypes (such as gene expression), especially when multiple phenotypes are involved.
Md. Bahadur Badsha, Audrey Qiuyan Fu
doaj   +1 more source

What to Do When Medical Evidence Can Only Be Generated Through Routine Data: An Example From Pediatric Oncology

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Children undergoing allogeneic stem cell transplantation often receive off‐label rituximab treatment for Epstein–Barr virus reactivation, using adult dosing without pediatric evidence. This project aims to develop a clinical decision support tool (CDSS) that provides evidence‐based dosing scenarios by analyzing real‐world patient data.
Birgit Burkhardt, Antje Walz, Dietrich Knoerzer   +2 more
wiley   +1 more source

Sex chromosome evolution in parasitic nematodes of humans

Nature Communications, 2020
Many nematode worms, including Caenorhabditis elegans have XX/XO sex determination, while other species have XY. The authors use a new genome assembly of the filarial parasite Brugia malayi and published data to show that nematode sex chromosome ...
Jeremy M. Foster, Alexandra Grote, John Mattick, Alan Tracey, Yu-Chih Tsai, Matthew Chung, James A. Cotton, Tyson A. Clark, Adam Geber, Nancy Holroyd, Jonas Korlach, Yichao Li, Silvia Libro, Sara Lustigman, Michelle L. Michalski, Michael Paulini, Matthew B. Rogers, Laura Teigen, Alan Twaddle, Lonnie Welch, Matthew Berriman, Julie C. Dunning Hotopp, Elodie Ghedin   +22 more
doaj   +1 more source

Stereotactic Body Radiation Therapy for Pediatric, Adolescent, and Young Adult Patients With Osteosarcoma: Local Control Outcomes With Dosimetric Analysis

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background/Objectives Osteosarcoma is a radioresistant tumor that may benefit from stereotactic body radiation therapy (SBRT) for locoregional control in metastatic/recurrent disease. We report institutional practice patterns, outcomes, toxicity, and failures in osteosarcoma patients treated with SBRT.
Jenna Kocsis, Shauna R. Campbell, Jonathan Jang, Eashwar Somasundaram, Chandana A. Reddy, Jacob G. Scott, Lilyana Angelov, Peter M. Anderson, Matteo Trucco, Zachary Burke, Lukas Nystrom, Nathan Mesko, Anthony Magnelli, Erin S. Murphy   +13 more
wiley   +1 more source

Proceedings of the Second Annual Conference of the MidSouth Computational Biology and Bioinformatics Society

BMC Bioinformatics, 2005
The MCBIOS 2004 conference brought together regional researchers and students in biology, computer science and bioinformatics on October 7th-9th 2004 to present their latest work.
Slikker William, Wren Jonathan D
doaj   +1 more source

Automatic Driver Drowsiness Detection Using Artificial Neural Network Based on Visual Facial Descriptors: Pilot Study

Nature and Science of Sleep, 2022
Papangkorn Inkeaw,1 Pimwarat Srikummoon,2,3 Jeerayut Chaijaruwanich,1,4 Patrinee Traisathit,2,3,5 Suphakit Awiphan,1,4 Juthamas Inchai,6 Ratirat Worasuthaneewan,7 Theerakorn Theerakittikul6,7 1Data Science Research Center, Department of Computer Science,
Inkeaw P, Srikummoon P, Chaijaruwanich J, Traisathit P, Awiphan S, Inchai J, Worasuthaneewan R, Theerakittikul T   +7 more
doaj  

Lifestyle Behaviors and Cardiotoxic Treatment Risks in Adult Childhood Cancer Survivors

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Higher doses of anthracyclines and heart‐relevant radiotherapy increase cardiovascular disease (CVD) risk. This study assessed CVD and CVD risk factors among adult childhood cancer survivors (CCSs) across cardiotoxic treatment risk groups and examined associations between lifestyle behaviors and treatment risks.
Ruijie Li, Raquel Revuelta Iniesta, Alan R. Barker, Dimitris Vlachopoulos, Tomáš Sláma, Christina Schindera, Fabiën N. Belle   +6 more
wiley   +1 more source

Hierarchical Multi-Bottleneck Classification Method And Its Application to DNA Microarray Expression Data [PDF]

, 2003
The recent development of DNA microarray technology is creating a wealth of gene expression data. Typically these datasets have high dimensionality and a lot of varieties.
Hsu, Wen Jing, Wong, Weng Fai, Xiong, Xuejian   +2 more
core  

VMEXT: A Visualization Tool for Mathematical Expression Trees

, 2017
Mathematical expressions can be represented as a tree consisting of terminal symbols, such as identifiers or numbers (leaf nodes), and functions or operators (non-leaf nodes).
B Gipp, B Gipp, BR Miller, HS Cohl, HS Cohl, M Schubotz, N Meuschke, Q Zhang, R Miner, S Kamali   +9 more
core   +1 more source

Algorithms for simulating human pre-mRNA splicing decisions [PDF]

, 2005
Thesis (M. Eng.)--Massachusetts Institute of Technology, Dept. of Electrical Engineering and Computer Science, 2005.Includes bibliographical references (leaves 37-38).In this thesis, I developed a program, ExonScan, to simulate constitutive human pre ...
Rolish, Michael E. (Michael Edward)
core