Results 71 to 80 of about 1,642,960 (338)

Sex chromosome evolution in parasitic nematodes of humans

Nature Communications, 2020
Many nematode worms, including Caenorhabditis elegans have XX/XO sex determination, while other species have XY. The authors use a new genome assembly of the filarial parasite Brugia malayi and published data to show that nematode sex chromosome ...
Jeremy M. Foster, Alexandra Grote, John Mattick, Alan Tracey, Yu-Chih Tsai, Matthew Chung, James A. Cotton, Tyson A. Clark, Adam Geber, Nancy Holroyd, Jonas Korlach, Yichao Li, Silvia Libro, Sara Lustigman, Michelle L. Michalski, Michael Paulini, Matthew B. Rogers, Laura Teigen, Alan Twaddle, Lonnie Welch, Matthew Berriman, Julie C. Dunning Hotopp, Elodie Ghedin   +22 more
doaj   +1 more source

Making tau amyloid models in vitro: a crucial and underestimated challenge

FEBS Letters, EarlyView.
This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley   +1 more source

Proceedings of the Second Annual Conference of the MidSouth Computational Biology and Bioinformatics Society

BMC Bioinformatics, 2005
The MCBIOS 2004 conference brought together regional researchers and students in biology, computer science and bioinformatics on October 7th-9th 2004 to present their latest work.
Slikker William, Wren Jonathan D
doaj   +1 more source

Automatic Driver Drowsiness Detection Using Artificial Neural Network Based on Visual Facial Descriptors: Pilot Study

Nature and Science of Sleep, 2022
Papangkorn Inkeaw,1 Pimwarat Srikummoon,2,3 Jeerayut Chaijaruwanich,1,4 Patrinee Traisathit,2,3,5 Suphakit Awiphan,1,4 Juthamas Inchai,6 Ratirat Worasuthaneewan,7 Theerakorn Theerakittikul6,7 1Data Science Research Center, Department of Computer Science,
Inkeaw P, Srikummoon P, Chaijaruwanich J, Traisathit P, Awiphan S, Inchai J, Worasuthaneewan R, Theerakittikul T   +7 more
doaj  

The intracellular domain of TLR2 is capable of high‐affinity Zn binding: possible outcomes for the receptor activation

FEBS Letters, EarlyView.
Toll‐like receptors (TLRs) are important in the innate immune system. This study explores the zinc‐binding ability of the TLR2 TIR domain (TLR2TIR). We found that TLR2TIR binds zinc with nanomolar affinity through its cysteine residues. Two of them, C673 and C713, are vital for receptor activation, indicating that zinc may play a role in initiating ...
Vladislav A. Lushpa, Cong Lin, Irina A. Talyzina, Marina V. Goncharuk, Eduard V. Bocharov, Alexander S. Arseniev, Xiaohui Wang, Sergey A. Goncharuk, Konstantin S. Mineev   +8 more
wiley   +1 more source

Hierarchical Multi-Bottleneck Classification Method And Its Application to DNA Microarray Expression Data [PDF]

, 2003
The recent development of DNA microarray technology is creating a wealth of gene expression data. Typically these datasets have high dimensionality and a lot of varieties.
Hsu, Wen Jing, Wong, Weng Fai, Xiong, Xuejian   +2 more
core  

The power of microRNA regulation—insights into immunity and metabolism

FEBS Letters, EarlyView.
MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto, Nicola Manfrini, Stefano Biffo   +2 more
wiley   +1 more source

Survey Paper on Emotion Recognition [PDF]

, 2016
Facial expressions give important information about emotions of a person. Understanding facial expressions accurately is one of the challenging tasks for interpersonal relationships. Automatic emotion detection using facial expressions recognition is now
Patil, S. (Sandeep), Shukla, P. (Prachi)
core  

Which Regular Expression Patterns are Hard to Match?

, 2016
Regular expressions constitute a fundamental notion in formal language theory and are frequently used in computer science to define search patterns. A classic algorithm for these problems constructs and simulates a non-deterministic finite automaton ...
Backurs, Arturs, Indyk, Piotr
core   +1 more source

A Variant of the Growing Neural Gas Algorithm for the Design of an Electric Vehicle Charger Network

Mathematics
The Growing Neural Gas (GNG) algorithm constitutes an incremental neural network model based on the idea of a Self-Organizing Map (SOM), that is, unsupervised learning algorithms that reduce the dimensionality of datasets by locating similar samples ...
Manuel Curado, Diego Hidalgo, Jose L. Oliver, Leandro Tortosa, Jose F. Vicent   +4 more
doaj   +1 more source