Results 31 to 40 of about 1,093,829 (219)

Comprehensive identification, characterization, and expression analysis of m6A methylation transferase gene family in maize (Zea mays L.)

Frontiers in Plant Science
N6-methyladenosine (m6A) RNA represents the most prevalent internal modification found in mRNA and plays a crucial role in stress response and developmental processes across various crop species.
Chunlei Li, Ming He, Xinyi Liu, Qingxue Lv, Xiaoming Yu, Xiaoxue Fan, Xia Bai, Jie Cong, Chuanbo Sun   +8 more
doaj   +1 more source

Functional conservation and divergence in plant-specific GRF gene family revealed by sequences and expression analysis

Open Life Sciences, 2022
Unique to plants, growth regulatory factors (GRFs) play important roles in plant growth and reproduction. This study investigated the evolutionary and functional characteristics associated with plant growth. Using genome-wide analysis of 15 plant species,
Meng Lingyan, Li Xiaomeng, Hou Yue, Li Yaxuan, Hu Yingkao   +4 more
doaj   +1 more source

Deep Sequencing of FLT3‐ITD Enables Response Evaluation and Post‐Treatment Monitoring in Childhood AML: An Exploratory Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background An internal tandem duplication in the gene encoding Fms‐like tyrosine kinase 3 (FLT3‐ITD) is associated with high relapse risk and poor prognosis in acute myeloid leukemia (AML) and plays a crucial role in treatment decisions. Measurable residual disease (MRD) analysis of FLT3‐ITD during and after treatment has shown prognostic ...
Sofie Johansson Alm, Bea Tornberg, Erik Delsing Malmberg, Henrik Hasle, Kristian Løvvik Juul‐Dam, Lars Palmqvist, Borhan R. Saeed, Giti Shah Barkhordar, Anastasia Soboli, Anna Staffas, Jonas Abrahamsson, Linda Fogelstrand   +11 more
wiley   +1 more source

Genome-wide analysis of RAD23 gene family and a functional characterization of AcRAD23D1 in drought resistance in Actinidia

Journal of Integrative Agriculture
UBL-UBA protein functions as a shuttle factor in the 26S ubiquitin degradation pathway, playing a critical role in plant growth and development, and responding to various biotic and abiotic stresses.
Xiaoli Zhang, Daolin Ye, Xueling Wen, Xinling Liu, Lijin Lin, Xiulan Lü, Jin Wang, Qunxian Deng, Hui Xia, Dong Liang   +9 more
doaj   +1 more source

Expression Profiling and Functional Analysis of Circular RNAs in Inner Mongolian Cashmere Goat Hair Follicles

Frontiers in Genetics, 2021
BackgroundInner Mongolian cashmere goats have hair of excellent quality and high economic value, and the skin hair follicle traits of cashmere goats have a direct and important effect on cashmere yield and quality.
Fangzheng Shang, Yu Wang, Rong Ma, Zhengyang Di, Zhihong Wu, Erhan Hai, Youjun Rong, Jianfeng Pan, Lili Liang, Zhiying Wang, Ruijun Wang, Zhihong Liu, Yanhong Zhao, Zhixin Wang, Jinquan Li, Jinquan Li, Jinquan Li, Yanjun Zhang   +17 more
doaj   +1 more source

Claudin‐6 Protein Expression in Atypical Teratoid/Rhabdoid Tumors Is Strongly Enriched in the Molecular Subgroup AT/RT‐TYR

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Claudin‐6 has emerged as a promising immunotherapeutic target, yet protein‐level data in atypical teratoid/rhabdoid tumors (AT/RTs) have been inconsistent. We analyzed 36 well‐characterized AT/RT samples and found membranous claudin‐6 protein expression in 58% of cases, with striking enrichment in the molecular subgroup AT/RT‐TYR (100%) and ...
Victoria E. Fincke, Christian Thomas, Michael C. Frühwald, Pascal D. Johann, Martin Hasselblatt   +4 more
wiley   +1 more source

Gene Expression Profile of Glioblastoma Multiforme Invasive Phenotype Points to New Therapeutic Targets

Neoplasia: An International Journal for Oncology Research, 2005
The invasive phenotype of glioblastoma multiforme (GBM) is a hallmark of malignant process, yet molecular mechanisms that dictate this locally invasive behavior remain poorly understood.
Dominique B. Hoelzinger, Luigi Mariani, Joachim Weis, Tanja Woyke, Theresa J. Berens, WendyS. McDonough, Andrew Sloan, Stephen W. Coons, Michael E. Berens   +8 more
doaj   +1 more source

The Role of Hematopoietic Cell Transplantation in Ataxia‐Telangiectasia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Ataxia‐telangiectasia (A‐T) is a DNA repair disorder characterized by neurodegeneration, immunodeficiency, and cancer predisposition. Hematopoietic cell transplantation (HCT) is an established therapy in related disorders such as Fanconi anemia (FA) and Nijmegen breakage syndrome (NBS), but its role in A‐T is unclear.
Laila Alkhouli, Seth Rotz, Masatoshi Takagi, Richa Sharma   +3 more
wiley   +1 more source

Protein expression profile and microRNA expression signature in estrogen receptor-positive and -negative breast cancers: report of two cases

Breast Cancer: Targets and Therapy, 2018
Yuko Tsunoda,1 Akiko Sasaki,2 Naomi Sakamoto,1 Kou Teraoka,1 Rie Nakagawa,1 Yoshitomo Koshida,1 Eisuke Fukuma1 1Department of Breast Surgery, Breast Center, Kameda Medical Center, Chiba, Japan; 2Department of Pharmacology, Showa University School of ...
Tsunoda Y, Sasaki A, Sakamoto N, Teraoka K, Nakagawa R, Koshida Y, Fukuma E   +6 more
doaj  

Genomic Analysis of LEA Genes in Carica papaya and Insight into Lineage-Specific Family Evolution in Brassicales

Life, 2022
Late embryogenesis abundant (LEA) proteins comprise a diverse superfamily involved in plant development and stress responses. This study presents a first genome-wide analysis of LEA genes in papaya (Carica papaya L., Caricaceae), an economically ...
Zhi Zou, Jingyuan Guo, Yujiao Zheng, Yanhua Xiao, Anping Guo   +4 more
doaj   +1 more source