Results 131 to 140 of about 135,054 (291)

Sequelae of child maltreatment: Umbrella synthesis of 148 meta‐analyses on the mental health correlates

JCPP Advances, EarlyView.
Our umbrella synthesis found strong, often equivalent, associations between child maltreatment and all examined mental health difficulties. Different types of maltreatment appear to have comparably negative effects on mental health. If replicated, these findings may cause us to reconsider conventional wisdom that suggests some forms of CM are less ...
Barry Coughlan, Robbie Duschinsky, Marian J. Bakermans‐Kranenburg, Lianne Bakkum, Guy C. M. Skinner, Alfred Markham, Helen Beckwith, Marinus H. van Ijzendoorn   +7 more
wiley   +1 more source

A New Liver Expression Quantitative Trait Locus Map From 1,183 Individuals Provides Evidence for Novel Expression Quantitative Trait Loci of Drug Response, Metabolic, and Sex-Biased Phenotypes

, 2021
A.S. Etheridge, P.J. Gallins, D. Jima, K.A. Broadaway, M.J. Ratain, E. Schuetz, E. Schadt, A. Schroder, C. Molony, Y. Zhou, K.L. Mohlke, F.A. Wright, F. Innocenti   +12 more
openalex   +1 more source

Allele-specific NKX2-5 binding underlies multiple genetic associations with human electrocardiographic traits. [PDF]

, 2019
The cardiac transcription factor (TF) gene NKX2-5 has been associated with electrocardiographic (EKG) traits through genome-wide association studies (GWASs), but the extent to which differential binding of NKX2-5 at common regulatory variants contributes
Benaglio, Paola, D'Antonio, Matteo, D'Antonio-Chronowska, Agnieszka, DeBoever, Christopher, Donovan, Margaret KR, Drees, Frauke, Frazer, Kelly A, Gaulton, Kyle J, Li, He, Ma, Wubin, Matsui, Hiroko, Rosenfeld, Michael G, Singhal, Sanghamitra, Smith, Erin N, Sotoodehnia, Nona, van Setten, Jessica, Yang, Feng, Young Greenwald, William W   +17 more
core  

Ophidiomycosis Prevalence and Disease Ecology in a Natrix tessellata (Laurenti, 1768) Population From Northern Italy

Journal of Experimental Zoology Part A: Ecological and Integrative Physiology, EarlyView.
ABSTRACT Fungal pathogens pose a growing threat to vertebrate biodiversity. In snakes, Ophidiomyces ophidiicola (Oo) has garnered particular concern, although its impact in Europe remains poorly understood. We conducted a season‐long, standardized survey of dice snakes (Natrix tessellata) along the northern shore of Lake Como (Italy) to quantify Oo and
Matteo Riccardo Di Nicola, Luca Colla, Kevin P Mulder, Federico Storniolo, Elin Verbrugghe, Giuseppe Esposito, Donato A. Grasso, Frank Pasmans, An Martel   +8 more
wiley   +1 more source

Integrative Genomics Reveals Causal Pleiotropy and Therapeutic Opportunities at the Interface of Acute Pancreatitis and Infection

Journal of Hepato-Biliary-Pancreatic Sciences, EarlyView.
ABSTRACT Background Understanding the genetic links between acute pancreatitis (AP) and its infectious comorbidities is crucial for prognosis and therapy, yet remains underexplored. Methods We conducted a comprehensive post‐GWAS analysis using large‐scale summary statistics for AP and 16 infectious diseases. To pinpoint pleiotropic genes, we integrated
Bo Zou, Hao Jiang, Jingsheng Ruan, Daifeng Yang, Xing Chen, Shanshan Cai, Xinglin Yi   +6 more
wiley   +1 more source

Expression Quantitative Trait Loci (eQTL) mapping for callose synthases in intergeneric hybrids of Citrus challenged with the bacteria Candidatus Liberibacter asiaticus

, 2021
Maiara Curtolo, Laís Moreira Granato, Tatiany Aparecida Teixeira Soratto, Maisa Curtolo, Rodrigo Gazaffi, Marco Aurélio Takita, Mariângela Cristofani–Yaly, Marcos Antônio Machado   +7 more
openalex   +1 more source

Reframing and Taming Uncertainty: A Qualitative Study on Self‐Affirmation Interventions for Supporting Coping With Entrepreneurs' Insecurity

Strategic Change, EarlyView.
ABSTRACT Self‐affirmation interventions (SAIs) have garnered increasing interest from both practitioners and scholars due to their potential to help working adults cope with uncertainty and job insecurity. This interest is particularly relevant for entrepreneurs, who frequently face high levels of uncertainty and lack the organizational support ...
Alexandra Jussli, Martin Schwarz
wiley   +1 more source

Comparative analysis of pomological and phytochemical characteristics in white‐ and red‐fleshed pitaya (Hylocereus spp.), with molecular docking insights into key bioactive compounds

Journal of the Science of Food and Agriculture, EarlyView.
Abstract BACKGROUND Cacti, including pitaya (Hylocereus spp.), are rich in antioxidants that will undoubtedly gain importance under ongoing climate change as water resources decline. Yet the molecular basis linking composition to antioxidant function remains incompletely defined. We compared white‐fleshed H. undatus and red‐fleshed H. polyrhizus across
Kerem Mertoglu, Annik Fischer, Sina Zargarchi, Melekber Sulusoglu Durul, Magdalena Köpsel, Erdi Can Aytar, Ibrahim Bulduk, Barıs Kaki, Tuba Esatbeyoglu   +8 more
wiley   +1 more source

MendelR: A One‐Stop R Toolkit for Mendelian Randomization Analysis

Med Research, EarlyView.
ABSTRACT MendelR is a fully automated R package specifically developed for Mendelian randomization (MR) studies, designed to address the technical challenges of causal inference in biomedical research. As a powerful causal inference method, Mendelian randomization can effectively reduce confounding bias in observational studies.
Xiaohong Ke, Kailai Li, Anqi Lin, Yasi Zhang, Peng Luo   +4 more
wiley   +1 more source

Defense heterosis as a novel plant protection strategy: From theory to breeding practice

New Plant Protection, EarlyView.
Defense heterosis, the enhanced disease resistance of hybrids compared to their parents, has evolved from early observations of hybrid vigor to a novel research concept. Advances are now clarifying its diverse genetic and molecular mechanisms across various plant–pathogen interactions.
Kaiqi Xu, Xue Li, Fangfang Li
wiley   +1 more source