Results 71 to 80 of about 11,262 (206)

An Analysis of Positive Politeness Strategy Used on Expressive Utterance in “The School for Good and Evil” Movie

open access: yesAcuity
This study investigates the use of positive politeness strategies in the movie The School for Good and Evil, utilizing Brown and Levinson's politeness theory (1987). By analyzing expressive utterances, the research examines how characters convey emotions,
Jazila Atsna, Santi Andriyani
doaj   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

open access: yesFEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

The Role of Expressive Abstraction in Creating a Mural Processing for the Map Square in the Dakahlia Governorate

open access: yesJournal of Architecture, Art & Humanistic Science
The most important thing that distinguishes art from all other human activities is that it goes beyond mere depiction of reality, as it contains a minimum of idealism, and transcends it on its familiar daily scale; This was one of the goals of the ...
Dr. Dina Yousri Soliman Dorgham
doaj   +1 more source

Vernacular Catholicism in Ireland: The Keening Woman

open access: yesReligions
The relationship between popular vernacular Catholicism and the more official liturgical variety has varied over centuries. Following the subjugation of Ireland by the late 17th century, and the institution of anti-Catholic proscriptions, the number of ...
Sean Williams, Lillis Ó Laoire
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

How the body tells the story: using the nonverbal cues of trauma between mothers and toddlers to mark a change in maternal attitudes during Clinician-Assisted Videofeedback Exposure Sessions

open access: yesFrontiers in Psychology
IntroductionThis study aims to examine what a form of video-based analysis of nonverbal communication: “Dyadic Attachment-based Nonverbal Communicative Expressions (DANCE)” can reveal about change in the bodies of interpersonal violence-exposed mothers ...
Suzi Tortora   +3 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

open access: yesFEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry   +9 more
wiley   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

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