Results 81 to 90 of about 6,811,260 (293)

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

Document Spanners: From Expressive Power to Decision Problems

open access: yesTheory of Computing Systems, 2017
We examine document spanners, a formal framework for information extraction that was introduced by Fagin, Kimelfeld, Reiss, and Vansummeren (PODS 2013, JACM 2015).
Dominik D. Freydenberger, Mario Holldack
semanticscholar   +1 more source

What can formal language theory do for animal cognition studies? [PDF]

open access: yesRoyal Society Open Science, 2020
Aniello De Santo, Jonathan Rawski
doaj   +1 more source

Modeling Hybrid Systems in the Concurrent Constraint Paradigm [PDF]

open access: yesElectronic Proceedings in Theoretical Computer Science, 2015
Hybrid systems, which combine discrete and continuous dynamics, require quality modeling languages to be either described or analyzed. The Concurrent Constraint paradigm (ccp) is an expressive declarative paradigm, characterized by the use of a common ...
Damián Adalid   +2 more
doaj   +1 more source

On the expressive power of semijoin queries [PDF]

open access: yesInformation Processing Letters, 2004
9 pages, to appear in Information Processing Letters; added results that more clearly delineate the expressive power of SA, added a section that discusses the impact of order on the expressive power of SA, deemphasized the discussion on the relationship with ...
Dirk Leinders   +2 more
openaire   +4 more sources

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Voicelessness and the Expressive Power of Omission

open access: yesS: I. M. O. N.
This article examines creative strategies for articulating the inexpressible and unsayable, with particular emphasis on the voicelessness surrounding violence against Jewish communities within the context of Soviet history and repression.
Vera Faber
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

The expressive power of quantum walks in terms of language acceptance [PDF]

open access: yesElectronic Proceedings in Theoretical Computer Science, 2014
Discrete time quantum walks are known to be universal for quantum computation. This has been proven by showing that they can simulate a universal quantum gate set.
Katie Barr, Viv Kendon
doaj   +1 more source

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

open access: yesFEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani   +3 more
wiley   +1 more source

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