Results 41 to 50 of about 69,680 (300)

Biophysical approaches for studying viral entry

open access: yesFEBS Letters, EarlyView.
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

The Military State of Valencia and the news about the moriscos’ expulsion [PDF]

open access: yes, 2018
A principis de setembre de 1609, els preparatius per a l’expulsió dels moriscos havien començat en secret i l’Estament Militar va començar a dubtar sobre ells. Després d’alguns dies i altres tants conflictes, la noblesa va decidir posicionar-se en contra
Fuertes Broseta, Miquel
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

In the shadow of dissidence: exploring the experiences of descendants of Czechoslovakian dissidents

open access: yesFrontiers in Psychology
IntroductionThe Communist Party’s reign in Czechoslovakia (1948–1989) saw the persecution of thousands of individuals. The State Security campaign “Asanace” (meaning “sanitation”) was conducted to expel critics of the regime from the country using ...
Nikola Doubková   +4 more
doaj   +1 more source

Weakening the nuclear envelope: Lamin B receptor in melanoma metastasis

open access: yesMolecular Oncology, EarlyView.
LBR‐driven nuclear fragility supports melanoma invasion. A: Melanocyte presents low LBR (Lamin B Receptor) levels, maintaining nuclear integrity and lamina‐chromatin tethering. B: During malignant progression, upregulation of LBR clusters at the INM (Inner Nuclear Membrane) during confined migration causes local lamina weakening and cholesterol ...
Francesca Lorenzini   +1 more
wiley   +1 more source

Adaptaciones y estrategias político-religiosas locales de un jesuita expulso: Diego León de Villafañe (1731-1830) y un conflicto teológico con el clero de San Miguel de Tucumán

open access: yesNuevo mundo - Mundos Nuevos, 2021
Between August 1804 and June 1807 a confrontation developed in San Miguel de Tucumán between some members of the Tucumán clergy and Diego León de Villafañe, a Jesuit who had managed to return from the exile imposed by the Spanish crown in 1767 to all the
Nicolás Hernán Perrone
doaj   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

Indicator B4A : suspension and expulsion. Somali

open access: yes, 2021
Title from PDF caption (viewed on December 28, 2021).This archived document is maintained by the State Library of Oregon as part of the Oregon Documents Depository Program.

core  

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

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