Results 151 to 160 of about 831,260 (309)

School Age Care Services in Australia

, 2019
School Age Care services in Australia are regarded as the fastest growing children care sec- tor. The changes in family circumstances such as longer working hours, families with both parents in full-time employment, single-parent families, changing ...
Cartmel, Jennifer
core   +1 more source

Extended reality in cardiovascular care: a systematic review

European Heart Journal - Digital Health
Abstract Extended reality (XR) is an emerging technology currently finding its way into various medical fields. This systematic review aimed to compile a comprehensive overview of the current data on XR in cardiovascular medicine. To identify the currently available evidence of the applications of XR in cardiology, we searched PubMed and
Dominika Kanschik, Raphael Romano Bruno, Michel E van Genderen, Patrick W Serruys, Tsung-Ying Tsai, Malte Kelm, Christian Jung   +6 more
openaire   +3 more sources

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Sarcopoenia in an integrated occupational project aimed at elderly patients with femoral fractures due to bony brittleness

Bone Reports, 2020
Ferdinando D'Amico, Rossella D'Amico
doaj   +1 more source

Growth and Development in Preterm Infants and Maternal Parenting Stress after WeChat-Based Extended Care.

Evid Based Complement Alternat Med, 2022
Zheng L, Zhu Z.
europepmc   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Intergenerational Transfers of Time and Public Long-term Care with an Aging Population [PDF]

In this paper, we use a two-period overlapping generations model to examine the behavior of an economy that incorporates intergenerational transfers of time. In the first part, we describe the dynamics and steady state of the economy in which there is no
Atsue Mizushima
core  

The use of mind mapping in health education in extended care for children with caries. [PDF]

J Int Med Res, 2020
Yang H, Gao XB, Li MH, Ye Q, Sun Y, Huang Y.   +5 more
europepmc   +1 more source