Results 191 to 200 of about 831,260 (309)

Intermediate Care Technicians-A Novel Workforce for Veterans Affairs Geriatric Emergency Departments

Journal of Geriatric Emergency Medicine, 2021
Colleen McQuown, Kristina Snell, Thomas Edes   +2 more
doaj  

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

A Random Parameter Logit model for modeling Health Care Provider Choice in Bolivia

In this paper we model health care provider choice in Bolivia with a Random Parameter Logit (RPL) using MECOVI data during the period 1999 and 2000. To our knowledge this is the first time that a RPL is used for modeling health care provider choice in ...
Canaviri, Jose
core  

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

Extended early childhood intervention and school achievement: Age 13 findings from the Chicago longitudinal study [PDF]

We evaluated the effects of participation in an extended program of compensatory education for a large sample of inner-city black children up to the seventh grade. The intervention is the Chicago Child-Parent Center and Expansion Program. Groups included
A. J. Reynolds, J. A. Temple
core  

Effect of Telehealth Extended Care for Maintenance of Weight Loss in Rural US Communities: A Randomized Clinical Trial.

JAMA Netw Open, 2020
Perri MG, Shankar MN, Daniels MJ, Durning PE, Ross KM, Limacher MC, Janicke DM, Martin AD, Dhara K, Bobroff LB, Radcliff TA, Befort CA.   +11 more
europepmc   +1 more source

Shared decision-making for people living with dementia in extended care settings: a systematic review. [PDF]

BMJ Open, 2018
Daly RL, Bunn F, Goodman C.
europepmc   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Mobile phone application for self-assessment of acute stroke patients: A tool for extended care and follow-up. [PDF]

Medicine (Baltimore), 2018
Chang H, Zhao J, Qiao Y, Yao H, Wang X, Li J, Liu J.   +6 more
europepmc   +1 more source