Results 101 to 110 of about 8,499 (170)

Ancestral Origin and Structural Characteristics of Non‐Syntenic Homologous Chromosomes in Abalones (Haliotis)

Molecular Ecology Resources, Volume 26, Issue 1, January 2026.
ABSTRACT Structural variation is increasingly recognised as a pivotal contributor to genomic diversity in marine invertebrates, yet its extent and evolutionary significance remain poorly characterised in many species. Haplotype‐phased genome assembly is an excellent resource for studying such variations by comparing homologous chromosomes.
Shotaro Hirase, Takashi Makino, Takeshi Takeuchi, Mitsutaka Kadota, Shigehiro Kuraku, Kiyoshi Kikuchi   +5 more
wiley   +1 more source

SenSeqNet: A Deep Learning Framework for Cellular Senescence Detection From Protein Sequences

Aging Cell, Volume 25, Issue 1, January 2026.
We present SenSeqNet, a deep learning framework that predicts cellular senescence directly from protein sequences. SenSeqNet integrates embeddings from the Evolutionary Scale Modeling(ESM‐2) with a hybrid LSTM–CNN architecture to capture both sequential and higher‐order structural features.
Hanli Jiang, Dongliang Deng, Yu Yuan, Jianyu Ren, Xin Yang, Siyi Liu, Bin Tan, Li Lin, Lubin Liu   +8 more
wiley   +1 more source

Lysine demethylase 4A is a centrosome‐associated protein required for centrosome integrity and genomic stability

The FEBS Journal, Volume 293, Issue 2, Page 396-417, January 2026.
KDM4A, a chromatin eraser, localizes to the centrosomes. Its demethylase activity is essential for maintaining centrosome number and integrity, independent of gene expression changes. Loss of KDM4A leads to centrosome amplification, pseudo‐bipolar spindle formation, and chromosome segregation errors, including micronuclei and chromatin bridges.
Pratim Chowdhury, Xiaoli Wang, Richard I. Han, Manga Motrapu, Ashley G. Boice, Yuya Nakatani, Sofia Vargas‐Hernandez, Julia F. Love, Claude Chew, Sandra L. Grimm, Dereck Mezquita, Frank M. Mason, Elisabeth D. Martinez, Cristian Coarfa, Cheryl L. Walker, Anna‐Karin Gustavsson, Ruhee Dere   +16 more
wiley   +1 more source

INEQUALITIES OF EXTENDED (p, q)-BETA AND CONFLUENT HYPERGEOMETRIC FUNCTIONS

, 2019
Shahid Mubeen, Kottakkaran Sooppy Nisar, Gauhar Rahman, Muhammad Arshad   +3 more
openalex   +2 more sources

RNA tomography reveals spatial gene expression maps of Arabidopsis thaliana roots infected with Heterodera schachtii

New Phytologist, Volume 249, Issue 1, Page 588-602, January 2026.
Summary Plant‐parasitic cyst nematodes, such as Heterodera schachtii, cause substantial crop losses world‐wide and induce specialized feeding structures in host roots, yet the molecular mechanisms underlying feeding structure initiation and development remain poorly understood.
Anna Pijnacker, Yuhao Wang, Jaap‐Jan Willig, Jonas Mars, Steffen Werner, Kelvin Adema, Geert Smant, Hendrik C. Korswagen, Jose L. Lozano‐Torres   +8 more
wiley   +1 more source

Diploid origins and early genome stabilization in the allotetraploid Arabidopsis suecica

New Phytologist, Volume 249, Issue 1, Page 524-538, January 2026.
Summary Polyploidization, followed by genome downsizing, is a recurrent evolutionary cycle that dramatically reshapes genome structure. Newly formed polyploids must quickly adjust their cell division machinery to maintain stable chromosome inheritance, while long‐term stabilization involves rediploidization, returning the genome to a diploid‐like state.
Robin Burns, Anna Glushkevich, Aboli Kulkarni, Uliana K. Kolesnikova, Filip Kolář, Alison Dawn Scott, Polina Yu. Novikova   +6 more
wiley   +1 more source

Coupling gene expression dynamics to cell size dynamics and cell cycle events: Exact and approximate solutions of the extended telegraph model. [PDF]

iScience, 2023
Jia C, Grima R.
europepmc   +1 more source

Analytic study and statistical enforcement of extended beta functions imposed by Mittag-Leffler and Hurwitz-Lerch Zeta functions. [PDF]

MethodsX
Abdulnabi FF, Al-Janaby HF, Ghanim F.
europepmc   +1 more source

EHE cell cultures are a platform for mechanistic and therapeutic investigation. [PDF]

Sci Rep
Scalora N, DeWane G, Drebot Y, Khan AA, Sinha S, Ghosh K, Robinson D, Cogswell P, Bellizzi AM, Snow AN, Breheny P, Chimenti MS, Tanas MR.   +12 more
europepmc   +1 more source

Exposure of iPSC-derived human microglia to brain substrates enables the generation and manipulation of diverse transcriptional states in vitro. [PDF]

Nat Immunol, 2023
Dolan MJ, Therrien M, Jereb S, Kamath T, Gazestani V, Atkeson T, Marsh SE, Goeva A, Lojek NM, Murphy S, White CM, Joung J, Liu B, Limone F, Eggan K, Hacohen N, Bernstein BE, Glass CK, Leinonen V, Blurton-Jones M, Zhang F, Epstein CB, Macosko EZ, Stevens B.   +23 more
europepmc   +1 more source