Results 231 to 240 of about 40,502 (261)

Comparative multi‐omics in female mice reveals tissue‐specific vulnerabilities to chronic alcohol intake

Alcohol, Clinical and Experimental Research, Volume 50, Issue 2, February 2026.
Using mice, we applied multi‐omics to compare liver and skeletal muscle after chronic alcohol consumption. The liver responded more strongly across genes, proteins, and metabolites, with a lowered PC:PE ratio. Muscle showed inflammation, extracellular matrix activation, impaired mitochondrial energetics, and an elevated PC:PE ratio. Lipidomics affected
Craig R. G. Willis, Muni Swamy Ganjayi, Austin M. Brown, Samantha E. Moser, Nathaniel J. Szewczyk, Brian C. Clark, Cory W. Baumann   +6 more
wiley   +1 more source

Synergistic intragenic epigenetic deregulation by IDH2 and SRSF2 mutations causes mis-splicing of key transcriptional regulators. [PDF]

Sci Adv
Telonis AG, Stanley RF, Adelman ER, Yoshimi A, Adele AA, Cruz A, Wiseman DH, Abdel-Wahab O, Figueroa ME.   +8 more
europepmc   +1 more source

Advanced Paternal Age Impacts Common Loci in the Sperm and Placenta DNA Methylomes

Andrology, Volume 14, Issue 2, Page 528-544, February 2026.
ABSTRACT Background Epidemiological studies have reported an association between advanced paternal age at conception and an increased risk of neurodevelopmental disorders in offspring, such as autism spectrum disorder. Evidence suggests that DNA methylation alterations in spermatozoa of older men may be transmitted to the feto‐placental unit and ...
Julia Barnwell, Sophia Rahimi, Sherri Lee Jones, Donovan Chan, Josée Martel, Sara Abdessamie, Catherine M. Herba, Jean R. Séguin, William D. Fraser, Celia M. T. Greenwood, Tuong‐Vi Nguyen, Tina C. Montreuil, Jacquetta Trasler   +12 more
wiley   +1 more source

ABCA7 variants impact phosphatidylcholine and mitochondria in neurons. [PDF]

Nature
von Maydell D, Wright SE, Pao PC, Staab C, King O, Spitaleri A, Bonner JM, Liu L, Yu CJ, Chiu CC, Leible D, Ni Scannail A, Li M, Boix CA, Mathys H, Leclerc G, Menchaca GS, Welch G, Graziosi A, Leary N, Samaan G, Kellis M, Tsai LH.   +22 more
europepmc   +1 more source

Effects of Seating Arrangements on Parliamentary Collaborations

Legislative Studies Quarterly, Volume 51, Issue 1, February 2026.
ABSTRACT Does parliamentary seating affect parliamentary behavior? In this paper, we dig into the question of whether spatial proximity affects the behavior of elected representatives. Using data from the 50th legislative period of the Swiss parliament and an inferential network model, we estimate the effects of different operationalizations of seating
Laurence Brandenberger, Teodora Bujaroska   +1 more
wiley   +1 more source

Plasma proteome adaptations during feminizing gender-affirming hormone therapy. [PDF]

Nat Med
Nguyen NNL, Celestra D, Angus LM, Mansell T, Shepherd R, Kim BW, Arman B, Cabau G, Crișan TO, Joosten LAB, Laberthonnière C, Burgner D, Tachedjian G, Mhlanga M, Davey RA, Pang KC, Cheung AS, Saffery R, Novakovic B.   +18 more
europepmc   +1 more source

Molecular Mechanism of ZjWRKY40‐zju‐miR157 Module Regulating Phytoplasma Tolerance in Jujube

Molecular Plant Pathology, Volume 27, Issue 2, February 2026.
SJP4JWB regulated the ZjWRKY40‐zju‐miR157 module to modulate the differential phytoplasma tolerance between phytoplasma‐susceptible genotype Fu and phytoplasma‐tolerant genotype T13. ABSTRACT Phytoplasma (‘Candidatus Phytoplasma’), a bacterial pathogen, is a significant plant health concern worldwide, resulting in substantial economic losses. In jujube
Changfeng Ai, Lixin Wang, Zhi Luo, Yunjie Wang, Xuan Zhao, Lili Wang, Jiaqi Sun, Kunyi Lv, Xueqing Yan, Haonan Cao, Noor Muhammad, Qiong Zhang, Mengjun Liu, Zhiguo Liu   +13 more
wiley   +1 more source

Cryo-EM structures of plant Augmin reveal coiled-coil assembly, antiparallel dimerization, and NEDD1 binding. [PDF]

Nat Commun
Ashaduzzaman M, Taheri A, Lee YJ, Tang Y, Mittal S, Guo F, Morcos F, Fried SD, Liu B, Al-Bassam J.   +9 more
europepmc   +1 more source

Meta-evolutionary exome analysis identifies novel type 2 diabetes mellitus genes in the UK Biobank and all of us. [PDF]

PLoS Genet
Wilhelm K, Asmussen J, Lee K, Samieinasab M, Asante E, Kimmel M, Lichtarge O.   +6 more
europepmc   +1 more source

Natural Variation of a PPR Coding Gene SST1 Confers Salt Tolerance During Soybean Domestication

Plant Biotechnology Journal, Volume 24, Issue 2, Page 831-855, February 2026.
ABSTRACT Soil salinity is one of the constraints that adversely affect seedling growth and limit soybean yield. Identifying salt tolerance genes and profiling their allele variants are crucial for elucidating the mechanisms underlying salt tolerance in soybean and enabling the genetic improvement of salt‐tolerant cultivars.
Hui Wang, Huifang Yuan, Yadi Wang, Weikang Xi, Xiaodi Wang, Ruiheng Tang, Qi Xu, Jiaying Li, Dongxu Liu, Qingyong Yang, Xutong Wang, Fanjiang Kong, Baohui Liu, Xia Li, Zhijuan Wang   +14 more
wiley   +1 more source