Results 71 to 80 of about 467,366 (265)

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

Molecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath, Irene A. George, Srikanth S. Manda, Prasanth Ariyannur, Ekta R. Dhawale, Raja Sekhar Kommu, Rajan Datar, Darshana Patil, Vinita Trivedi, Manisha Singh, Kumar Prabhash, Sewanti Limaye, Richa Chauhan, Prashant Kumar   +13 more
wiley   +1 more source

Approximate Ginzburg-Landau solution for the regular flux-line lattice. Circular cell method

, 2001
A variational model is proposed to describe the magnetic properties of type-II superconductors in the entire field range between $H_{c1}$ and $H_{c2}$ for any values of the Ginzburg-Landau parameter $\kappa>1/\sqrt{2}$.
A. A. Abrikosov, A. Aburto, A. E. Koshelev, A. I. Larkin, A. L. Fetter, A. L. Rakhmanov, A. Nugroho, A. S. Mel’nikov, A. S. Mel’nikov, C.-R. Hu, D. Ihle, D. Ihle, D. N. Zheng, D. Saint-James, E. A. Shapoval, E. H. Brandt, E. H. Brandt, E. H. Brandt, E. H. Brandt, E. H. Brandt, H.-J. Kim, H.-J. Kim, I. G. de Oliveira, J. H. Gohng, J. R. Clem, J. R. Clem, J. Rammer, J. Rammer, J. Sok, K. I. Kugel, M. Abramowitz, M. M. Doria, M. Xu, M. Y. Cheon, M.-S. Kim, M.-S. Kim, P. G. de Gennes, Q. Li, R. J. Watts-Tobin, S.-I. Lee, V. G. Kogan, V. G. Kogan, W. M. Kleiner, W. V. Pogosov, W. V. Pogosov, Y. C. Kim, Y. Zhuo, Z. Hao, Z. Hao, Z. Hao   +49 more
core   +1 more source

New exact solutions of cubic nonlinear schrödinger equation by using extended trial equation method

, 2020
Bu çalışmada, kısmi türevli diferansiyel denklemlerin tam çözümlerinin elde edilmesine olanak sağlayan genişletilmiş deneme denklem yöntemi incelenmiştir. Önerilen bu yöntem kübik lineer olmayan Schrödinger denklemine uygulanmış ve farklı yeni tam çözümleri elde edilmiştir.
PANDIR, Yusuf, AĞIR, Tural
openaire   +2 more sources

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

Molecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu, Jianlei Zhao, Aaban Asfar Azmi, Avanti Gupte, Jenna Thibodeau, Shuang Liu, Jinli Yang, Guan Wang, Holly Edwards, Lisa A. Polin, Juiwanna Kushner, Sijana H. Dzinic, Kathryn White, Julie Boerner, Maik Hüttemann, Jay Yang, Yue Wang, Jeffrey W. Taub, Yubin Ge   +18 more
wiley   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

A Density Matrix Algorithm for 3D Classical Models

, 1998
We generalize the corner transfer matrix renormalization group, which consists of White's density matrix algorithm and Baxter's method of the corner transfer matrix, to three dimensional (3D) classical models.
Affleck I., Baxter R. J., Baxter R. J., Bethe H. A., Carlon Enrico, Fannes M., Fannes M., Fannes M., Hida K., Kikuchi R., Klümper A., Kramers H. A., Niggemann H., Nightingale N. P., Nishino T., Nishino T., Nishino T., Nishino T., Rommer S., Sierra G., White S. R., White S. R., White S. R., Östlund S.   +23 more
core   +1 more source

Feasibility of a ctDNA multigenic panel for non‐small‐cell lung cancer early detection and disease surveillance

Molecular Oncology, EarlyView.
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande, Marcela de Oliveira Silva, Mariana Bisarro dos Reis, Rodrigo de Oliveira Cavagna, Luciane Sussuchi, Icaro Alves Pinto, Natalia Zampieri Pontes, Rodrigo Sampaio Chiarantano, Flavio Augusto Ferreira da Silva, Pedro de Marchi, Letícia Ferro Leal, Rui M. Reis   +11 more
wiley   +1 more source

Ab initio computations of molecular systems by the auxiliary-field quantum Monte Carlo method

, 2017
The auxiliary-field quantum Monte Carlo (AFQMC) method provides a computational framework for solving the time-independent Schroedinger equation in atoms, molecules, solids, and a variety of model systems.
Motta, Mario, Zhang, Shiwei
core   +1 more source

Tumor and germline testing with next generation sequencing in epithelial ovarian cancer: a prospective paired comparison using an 18‐gene panel

Molecular Oncology, EarlyView.
Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard, Cristina Mitric, Melanie Care, Tracy L. Stockley, Raymond H. Kim, Jeanna McCuaig, Blaise Clarke, Laura Ranich, Clare Sheen, Sarah E. Ferguson, Liat Hogen, Taymaa May, Marcus Q. Bernardini   +12 more
wiley   +1 more source

The Effect of Substituting Wheat Straw with Sugarcane Bagasse on Nutrient Digestibility, Blood Parameters, and Performance in Fattening Zandi Lambs [PDF]

پژوهشهای تولیدات دامی
Extended Abstract Background: The production of lignocellulosic materials from agricultural and industrial activities is substantial worldwide, representing the most abundant renewable energy source on earth.
Mohammad Doosti Fard, Mohammad Ali Norouzian   +1 more
doaj