Results 131 to 140 of about 206,308 (195)
α‐Synuclein aggregation landscape from phase separation to neurotoxic intermediates
FEBS Letters, EarlyView.Alpha‐synuclein aggregation in Parkinson's disease involves a complex landscape of transient intermediates, including oligomers, fibrils and liquid–liquid phase separation (LLPS). A view is emerging in which LLPS maturation into solid‐like condensates may contribute to the formation of neurotoxic species.
Silvia Arino +2 more
wiley +1 more source
La integración de los Programas Nacionales de Extensión Universitaria [PDF]
, 2014 El trabajo que se presenta está dirigido a realizar una propuesta, que desde las asignaturas de la disciplina Educación artística y Cultura General, permita dar solución al siguiente problema conceptual metodológico: la integración de los Programas ...
Marín Rodriguez, Carmen
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FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
, 2018 Durante 1998 dimos un fuerte apoyo desde la Presidencia de la Cámara de Diputados de la Provincia a los distintos programas que se desarrollan desde la Secretaría de Extensión Universitaria de la UNLP.
Ferro, Francisco
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Universidad y pueblos originarios: la extensión como eje articulador [PDF]
, 2015 Fil: Abduca, Ricardo G. Universidad de Buenos Aires. Facultad de Filosofía y Letras; ArgentinaFil: González, Crispina. Universidad de Buenos Aires. Facultad de Filosofía y Letras; ArgentinaFil: Iñigo Carrera, Valeria.
Iñigo Carrera, Valeria +7 more
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Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
FEBS Letters, EarlyView.Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley +1 more source
Agronomía Colombiana, 1995 Community participation into agroforestry systems research and extensión is a barrier for the practical development of this type of projects. The incorporation of the tree component has been traditionally took in account just as a reforestation or soil ...
Argüello Arias Heliodoro
doaj
Estrategia para la formación de un promotor de salud universitario auténtico desde la extensión universitaria [PDF]
, 2014 Para las universidades cubanas, en la actualidad, uno de los retos fundamentales está relacionado con la transformación de la gestión del proceso de la Extensión Universitaria.
Parrado Alvarez, Marianela +2 more
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