Results 211 to 220 of about 2,301,565 (248)

Neglected Ruptures of the Patellar Tendon: Report of Three Cases in the Orthopedic Trauma Department of Dalal Jamm Hospital, Dakar. [PDF]

J Orthop Case Rep
Diop M, Sow M, Dembele B, Daffé M, Diop B, Sané AD.   +5 more
europepmc   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Honrar, Honra Panel en Homenaje al Aniversario 85 del natalicio del Ministro Dr. Sergio del Valle Jiménez

Revista Habanera de Ciencias Médicas, 2012
María del Carmen Amaro Cano, Henoch Garriga, Helenio Ferrer Gracia, Carlos Scorza Sánchez, Fontaine Ortiz, Ernesto Méndez Calzadilla, Héctor Terry Molinert   +6 more
doaj  

Strengthening human infrastructure for smart farming through competency-based assessment of extension agents in precision agriculture. [PDF]

Sci Rep
Lee CL, Orton G, Oliveira L.
europepmc   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Relationship Between Knee Muscle Strength Symmetry and Lower Limb Landing Mechanics Following ACL Reconstruction. [PDF]

Sports Med Open
Yang K, Xue B, Ma X, Wang X, Zhao Y, Yang C, Zhou Z, Zheng L.   +7 more
europepmc   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Primary End-to-End Repair of Subacute Extensor Hallucis Longus Tendon Rupture Supported by a Preserved Extensor Hallucis Capsularis: A Case Report. [PDF]

Case Rep Orthop
Inoue R, Suzuki Y, Hamasaki M, Tsukuda Y, Hiratsuka S, Ura K, Ogawa T, Matsuoka M, Iwasaki K, Onodera T, Kondo E, Iwasaki N.   +11 more
europepmc   +1 more source