Results 51 to 60 of about 206,308 (195)

La verdad y la justicia frente a la prueba en el proceso penal

open access: yesJusticia, 2015
Resumen El articulo 361 del Código de Procedimiento Penal prohibe de manera ab- soluta al juez del conocimiento decretar pruebas de oficio, restringiendo la bus- queda de la verdad y la justicia; y por ello, en esta investigación, se pretende ...
Maximo Vicu   +1 more
doaj   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Resignificación de la extensión a 100 años de la Reforma Universitaria de 1918

open access: yes, 2018
Este artículo pretende reflexionar sobre los sentidos que ha adquirido la extensión´ universitaria en el contexto latinoamericano en las proximidades del centenario de la Reforma Universitaria.
Menéndez, Gustavo
core   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Evaluation of the negative expectations and type of suicide risk in students of 9°, 10° and 11° grade of an educational institution of the department of Quindío

open access: yesDuazary, 2016
This empirical and analytical study follows a descriptive - transversal design in order to assess the negative expectations and risk of suicide in students of 9°, 10° and 11° year of an educational institution in the Department of Quindío, counting with ...
Juan Gonzales-Portillo   +3 more
doaj  

Escuela de Turismo [PDF]

open access: yes, 2018
Actividades de extensión realizadas como parte de la formación dual.Número especial: Balance de Gestión 1998-2001/Propuestas para la Gestión 2001-2004.Secretaría de ...
Secretaría de Extensión
core  

La extensión universitaria argentina desde la promoción y evaluación estatal

open access: yes, 2018
Si bien desde la Reforma Universitaria (1918) se considera a la extensión universitaria como una función central de la universidad junto a la docencia y la investigación, en la práctica se la desarrolló en menor medida.Con la sanción de la Ley de ...
Gómez, Julieta Clara   +1 more
core   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

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