Summary Chronic lymphocytic leukaemia (CLL) primarily affects elderly patients with comorbidities, yet real‐world data on acalabrutinib, a second‐generation Bruton's Tyrosine Kinase (BTK) inhibitor, remain limited outside clinical trials, particularly in Italy.
Andrea Duminuco +21 more
wiley +1 more source
Thoracolumbar labour epidural analgesia in a parturient with permanent gluteal silicone-like biopolymer infiltration. [PDF]
Foggi Viligiardi T +3 more
europepmc +1 more source
Imagination Will Not Be Automized: On AI Image Generators and Epistemic Oppression
Constellations, EarlyView.
Sarah Abel
wiley +1 more source
Summary Ruxolitinib remains first‐line standard of care for symptomatic myelofibrosis, but resistance/intolerance develops in most patients. Three Janus kinase inhibitors (JAKis) have entered the post‐ruxolitinib space via distinct pivotal trials. We systematically searched prospective trials evaluating JAKi in refractory adults with myelofibrosis ...
Andrea Duminuco +8 more
wiley +1 more source
External Auditory Canal Metastasis of Colorectal Adenocarcinoma: A Comprehensive Case Report. [PDF]
Sissa L +5 more
europepmc +1 more source
International Delphi consensus on feminising genital surgery in assigned‐male‐at‐birth individuals
Objective To achieve an international expert consensus among surgeons on the indications, contraindications, and perioperative management of feminising genital surgery (FGS) for assigned‐male‐at‐birth (AMAB) individuals, using a Delphi process. Methods A two‐round on‐line Delphi survey (May–July 2025) followed by a final consensus meeting (September ...
Marta Pezzoli +30 more
wiley +1 more source
Safe to Spare? Predictors of Oncological Safety for Nerve-Sparing Technique during Robot-Assisted Radical Prostatectomy in High-Risk Prostate Cancer. Insight from a High Volume Center with Centralized mpMRI Review. [PDF]
Lambertini L +20 more
europepmc +1 more source
Molecular heterogeneity and prognostic biomarkers in primary meningeal melanocytic tumors
Integrated molecular profiling reveals biological heterogeneity among primary meningeal melanocytic tumors, identifying intermediate‐grade PMMT subgroups with distinct recurrence risk. Molecular alterations including SF3B1 mutations and chromosome 8q gains support prognostic stratification, while PRKAR1A alterations and chromosome 17/21q losses aid ...
Rosina Paterra +6 more
wiley +1 more source
Spectral Precision: The Added Value of Dual-Energy CT for Axillary Lymph Node Characterization in Breast Cancer. [PDF]
Guerrini S +11 more
europepmc +1 more source
Visual Cues for Logical Reasoning about Text Enhance Metacognitive Sensitivity
Abstract An important part of critical thinking is analyzing the logical structure of inferences made in text, such as checking whether if–then rules appearing in legal regulations or scientific arguments are applied correctly. Metacognitive sensitivity, defined as feeling confident about one's correct answers and uncertain about incorrect ones, is an ...
A. Schlieder, J. Rummel, F. Sadlo
wiley +1 more source

