Results 111 to 120 of about 2,759,551 (297)

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

To: Physicians : from: Extension Specialists, Department of Human Nutrition and Foods

open access: yes, 1989
A letter to physicians from Extension specialists on Extension's weight control education program for adults ...

core  

On Extension Of Functors

open access: yes, 2011
A.Chigogidze defined for each normal functor on the category Comp an extension which is a normal functor on the category Tych. We consider this extension for any functor on the category Comp and investigate which properties it preserves from the definition it preserves from the definition of normal functor.
Karchevska, L., Radul, T.
openaire   +3 more sources

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Extensive and Non-extensive Thermodynamics

open access: yesActa Physica Polonica B, 2016
This research addresses extensive and non-extensive thermodynamics. A comparison between the entropy for both different statistics are pre- sented. The non-extensive parameter, entropic index q , is discussed. We attempt to explore the limit of the non-extensive parameter by comparing the theoretical results with lattice and the available experimental ...
openaire   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Effective service: Some 1930 results showing the value of county farm and home demonstration agency work

open access: yes, 1930
This document summarizes various statistics about Alabama agriculture and farm life for 1930 to demonstrate the value to Alabama of the Extension Service.
Alabama Polytechnic Institute. Extension Service
core  

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

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