Results 211 to 220 of about 6,125,058 (320)

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

Full Issue, Volume 4, Number 1

Journal of Human Sciences and Extension, 2016
Journal of Human Sciences and Extension
doaj  

Clinical and Radiographic Outcomes of the Wrap-Around Extension Block Pinning Technique for Bony Mallet Fingers. [PDF]

Cureus
Israeli R, Cohen T, Gannot G, Avraham D, Oron A.   +4 more
europepmc   +1 more source

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

Molecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad, Mahmood Hachim, Tom Bertin, Karolina Penderecka, Rifat Hamoudi, Saif Khan, Rui Henrique, Natalie Bergmoser, Manit Arya, Kalle Sipila, Matteo Vietri Rudan, Asif Muneer, Aamir Ahmed   +12 more
wiley   +1 more source

Full Issue, Volume 1, Number 2

Journal of Human Sciences and Extension, 2013
Journal of Human Science and Extension
doaj  

Recognition of unnatural base pairs by a eukaryotic DNA polymerase enables universal sequencing of an expanded genetic alphabet. [PDF]

Nucleic Acids Res
Luo H, Du Y, Sun L, Ye F, Ma J, Wang X, Wang Y, Chen T.   +7 more
europepmc   +1 more source

S7A:4 Reduction of systemic lupus flares by atacicept in a randomised, placebo-controlled, phase iib study (address ii) and its extension study [PDF]

, 2018
DJ Wallace, David Isenberg, Amy Kao, Cristina Vazquez‐Mateo, Patricia Fleuranceau-Morel, Peter Chang, JT Merril   +6 more
openalex   +1 more source

Strength through diversity: how cancers thrive when clones cooperate

Molecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken, Maartje Witsen, Emile E. Voest, Krijn K. Dijkstra   +3 more
wiley   +1 more source

Full Issue, Volume 2, Number 3

Journal of Human Sciences and Extension, 2014
Journal of Human Sciences and Extension
doaj  

Robotic-Assisted Medial Epicondylar Osteotomy and Dual Fixation Technique During Total Knee Arthroplasty for Severe Varus Deformity. [PDF]

Arthroplast Today
Hulse N.
europepmc   +1 more source