Results 81 to 90 of about 2,213,684 (316)
Virginia Cooperative Extension Organizational Chart
This document is an organizational chart of Virginia Cooperative Extension personnel.title from VCE publications page; document revised July ...
Jones, Edwin J.
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Tau acetylation at K331 has limited impact on tau pathology in vivo
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Virginia Cooperative Extension Peer Reviewer Feedback Form
This document provides guidelines for reviewing quality and accuracy of text, and illustrations in manuscripts under consideration for publication by Virginia Cooperative ...
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Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Virginia Cooperative Extension Organizational Chart
This document is an organizational chart of Virginia Cooperative Extension personnel.title from VCE publications page; document revised August ...
Jones, Edwin J.
core
Field Crops PMG ' Insect control, 2021
This is a chapter of the 2021 Field Crops PMG. The Virginia Pest Management Guide (PMG) series lists options for management of major pests: diseases, insects, nematodes, and weeds.
Taylor, Sally V., Laub, Curtis A.
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Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
This paper examines the emergence of underground architecture extensions in Japan as a form of built heritage preservation. It positions this trend within the broader spectrum of Japanese conservation practices by tracing the evolution preservation ...
Waddah Dridi, Takahiro Taji
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source

