Results 31 to 40 of about 240 (176)

Performance of the SABAT Neutron-Based Explosives Detector Integrated with an Unmanned Ground Vehicle: A Simulation Study

Sensors, 2022
The effective and safe detection of illicit materials, explosives in particular, is currently of growing importance taking into account the geopolitical situation and increasing risk of a terrorist attack. The commonly used methods of detection are based
Michał Silarski, Marek Nowakowski
doaj   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Comprehensive Performance Evaluation of Insulation Materials for Low-Carbon Renovation of Enclosure Structures in Old Communities Based on Cloud Model and Matter–Element Extension Method

Sustainability
The selection of insulation materials during the renovation of enclosure structures in old communities significantly impacts project quality, cost, and carbon emissions. Many insulation materials currently in use only meet energy-saving standards as required by design specifications, often neglecting important aspects such as ancillary construction ...
Zheng, Jieshu, Lei, Hua, Lu, Yixuan, Xiong, Sheng   +3 more
openaire   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source

Blood-Sucking Fly Icosta ardeae – Its Distribution and Probable Role in Circulation of West-Nile FeverVirus

Проблемы особо опасных инфекций, 2013
Communication comprises materials on distribution of blood-sucking fly, Icosta ardeae, in the territory of the Russian Federation and bordering states. Based on the analysis of literature data, collection assets, and personal investigations assumed has ...
A. V. Matyukhin, A. N. Matrosov, A. M. Porshakov, A. A. Kuznetsov   +3 more
doaj   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

ENHANCING TECHNICIAN EDUCATION THROUGH INSTRUCTIONAL MATERIALS DEVELOPMENT IN DRAFTING, CONSTRUCTION, WELDING, AND ELECTRONICS PROCESSES USING DMAIC PRINCIPLES TOWARD SUSTAINABLE COMMUNITY EXTENSION PROGRAMS

Cognizance Journal of Multidisciplinary Studies
This study aimed to enhance technician education through the development of improved instructional materials in Drafting, Construction, Welding, and Electronics Processes by applying the DMAIC (Define, Measure, Analyze, Improve, Control) framework. The initiative was anchored on the need to address persistent gaps in instructional content, particularly
Redjie D. Arcadio, Marlyn G. Blanco, Marry May T. Lava, Fransisco L. Masicampo II, Wilbert T. Arañez, Michael D. Dunggon, Jiffrey Labang   +6 more
openaire   +1 more source

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

FEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani, Konstantinos Spanopoulos, Zoi Piperigkou, Nikos K. Karamanos   +3 more
wiley   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source