Results 141 to 150 of about 974,499 (305)

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

An Introduction to Growing Christmas Trees in Virginia

open access: yes, 2016
Provides a broad overview of Christmas tree production in Virginia. Potential growers should certainly seek more detailed information from county foresters and Extension agents, as proper planning can be the key to a successful ...
Peer, Kyle
core  

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

Informação e Desenvolvimento Rural: o caso de produtores rurais assentados em Vitória de Santo Antão (PE)

open access: yesDesenvolvimento em Questão, 2010
This research aims to investigate how information is transmited in family farms, and how the use of information can help to improve agricultural productivity, specially with technical improvements in cassava production in rural areas, such as Vitória de ...
Leonardo Rodrigues Ferreira   +1 more
doaj  

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

open access: yesMolecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain   +10 more
wiley   +1 more source

Flue-cured tobacco variety information for 1975

open access: yes, 1974
Presents information that may be helpful in choosing the best varieties of flue-cured tobacco to meet specific production ...
Jones, James L.   +2 more
core  

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Information-seeking behaviour of Iranian extension managers and specialists

open access: yesInformation Research: An International Electronic Journal, 2005
Introduction. We report an investigation designed to explore information-seeking behaviour of extension managers and specialists in Iran, and to identify the factors that correlate with their information-seeking behaviour. Method.
Gholamreza Pezeshki-Rad, Naser Zamani
doaj  

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

Producing sheep milk cheese

open access: yes
Facts and recommendations in this publication may no longer be valid. Please look for up-to-date information in the OSU Extension Catalog: http://extension.oregonstate.edu ...
Nashnush, Hani   +2 more
core  

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